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Data for identification of porcine X-chromosome inactivation center XIC by genomic comparison with human and mouse XIC

机译:通过与人和小鼠XIC的基因组比较来鉴定猪X染色体失活中心XIC的数据

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摘要

The data included in this article shows homologies of genes in porcine X-chromosome inactivation center, XIC, to each orthologue in human and mouse XIC. Open sequences of XIC-linked genes in human and mouse were compared to porcine genome and sequence homology of each orthologue to porcine genome was calculated. Sequence information of porcine genes encoded in the genomic regions having sequence homology with the human XIC-linked genes and their 2 Kb upstream regions were downloaded. Obtained information was used to design primer pairs for expression and methylation pattern analyses of XIC-linked genes in pigs. The data represented in here is related and applied to the research article entitled “Dosage compensation of X-chromosome inactivation center, XIC,-linked genes in porcine preimplantation embryos: Non-chromosome wide initiation of X-chromosome inactivation in blastocysts”, published in Mechanisms of Development Hwang et al., 2015 .
机译:本文包含的数据显示了猪X染色体失活中心XIC与人类和小鼠XIC中每个直向同源物的基因同源性。将人和小鼠中XIC连锁基因的开放序列与猪基因组进行比较,并计算每个直向同源物与猪基因组的序列同源性。下载了与人XIC连接的基因及其2 Kb上游区域具有序列同源性的基因组区域中编码的猪基因的序列信息。获得的信息用于设计引物对,用于猪中XIC连锁基因的表达和甲基化模式分析。此处表示的数据相关并应用于题为“猪植入前胚胎中X染色体失活中心,XIC连锁基因的剂量补偿:胚泡中X染色体失活的非染色体广泛启动”的研究文章,发展机制Hwang等,2015。

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