Lymphatic Vessel Density and Vascular Endothelial Growth Factor Expressionin Squamous Cell Carcinomas of Lip and Oral Cavity: A Clinicopathological Analysis withImmunohistochemistry Using Antibodies to D2-40 VEGF-C and VEGF-D

摘要

BackgroundSquamous cell carcinoma (SCC) of the oral region often metastasizes to the cervical lymph nodes. To investigate whether the risk of cervical lymph node metastasis are predictable through lymphatic vessel density (LVD) and vascular endothelial growth factor (VEGF) expression, we assessed the relationship between LVD and clinicopathological parameters, and VEGF expression in SCC of the oral region.