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High frequency of CD34+CD38-/low immature leukemia cells is correlated with unfavorable prognosis in acute myeloid leukemia

机译：CD34 + CD38- /低度未成熟白血病细胞的高频率与急性髓细胞性白血病的不良预后相关

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AIMTo evaluate the importance of the CD34+CD38- cell population when compared to the CD34+CD38+/low and CD34+CD38+/high leukemic cell sub-populations and to determine its correlations with leukemia characteristics and known prognostic factors, as well as with response to therapy and survival.

机译：目的与CD34 + CD38 + /低和CD34 + CD38 + /高白血病细胞亚群相比，评估CD34 + CD38-细胞群的重要性，并确定其与白血病特征，已知预后因素以及反应的相关性治疗和生存。

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期刊名称 World Journal of Stem Cells
作者
Adriana Plesa; Charles Dumontet; Eve Mattei; Ines Tagoug; Sandrine Hayette; Pierre Sujobert; Isabelle Tigaud; Marie Pierre Pages; Youcef Chelghoum; Fiorenza Baracco; Helene Labussierre; Sophie Ducastelle; Etienne Paubelle; Franck Emmanuel Nicolini; Mohamed Elhamri; Lydia Campos; Claudiu Plesa; Stéphane Morisset; Gilles Salles; Yves Bertrand; Mauricette Michallet; Xavier Thomas;
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作者单位

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年(卷),期 2017(9),12
年度 2017
页码 227–234
总页数 9
原文格式 PDF
正文语种
中图分类细胞生物学;
关键词
CD34+CD38-/low Immunophenotyping Leukemic stem cells Acute myeloid leukemia Prognosis;

机译：CD34 + CD38- /低;免疫分型;白血病干细胞;急性髓性白血病;预后;

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专利

1. High proportion of leukemic stem cells at diagnosis is correlated with unfavorable prognosis in childhood acute myeloid leukemia. [J] . Witte KE, Ahlers J, Schafer I, Pediatric Hematology and Oncology . 2011,第1a4期

机译：诊断时白血病干细胞比例高与儿童急性髓性白血病的不良预后有关。
2. CD11b expression correlates with monosomal karyotype and predicts an extremely poor prognosis in cytogenetically unfavorable acute myeloid leukemia [J] . ChenM.-H., AtenafuE., CraddockK.J., Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis . 2013,第2期

机译：CD11b表达与染色体核型有关，并预测在细胞遗传学上不利的急性髓性白血病的预后极差
3. Expression of indoleamine 2,3-dioxygenase in leukemic cells indicates an unfavorable prognosis in acute myeloid leukemia patients with intermediate-risk cytogenetics [J] . Fukuno Kenji, Hara Takeshi, Tsurumi Hisashi, Leukemia and lymphoma . 2015,第5期

机译：吲哚胺2,3-双加氧酶在白血病细胞中的表达表明具有中等风险细胞遗传学的急性髓性白血病患者预后不良
4. Protein Network Related to Unfavorable Prognosis in Acute Myeloid Leukemia [C] . L.F. Restrepo, S. Rothlisberger Latin American Congress on Biomedical Engineering . 2017

机译：蛋白质网络与急性髓性白血病的不利预后相关
5. Loss of Egr1 plays a role in murine leukemogenesis and may play a role in the development of acute myeloid leukemia and therapy-related acute myeloid leukemia. [D] . Joslin, John M. 2006

机译：Egr1的丢失在小鼠白血病的发生中起作用，并且可能在急性髓细胞性白血病和与治疗有关的急性髓细胞性白血病的发展中起作用。
6. Indoleamine 23-dioxygenase-1 (IDO1) expression by childhood acute myeloid leukemias inhibits T-cell production of IFN-γ and confers an unfavorable prognosis [O] . Sergio Rutella, Valentina Folgiero, Perla Filippini, 2013

机译：儿童急性髓细胞性白血病中吲哚胺23-二加氧酶-1（IDO1）的表达抑制IFN-γ的T细胞产生并给预后带来不利影响
7. Indoleamine 2,3-dioxygenase-1 (IDO1) expression by childhood acute myeloid leukemias inhibits T-cell production of IFN-γ and confers an unfavorable prognosis [O] . Sergio Rutella, Valentina Folgiero, Perla Filippini, 2013

机译：儿童急性髓细胞性白血病中吲哚胺2，3-二加氧酶-1（IDO1）的表达抑制IFN-γ的T细胞产生，并给预后带来不利影响

High frequency of CD34+CD38-/low immature leukemia cells is correlated with unfavorable prognosis in acute myeloid leukemia

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