Hereditary Angioedema: 454 Efficacy of Icatibant Versus Fresh Frozen Plasma for Attacks of Hereditary Angioedema: Analysis of Indivudual Symptoms by Attack Site

摘要

BackgroundHereditary angioedema (HAE) is a rare disorder characterized by funcional deficiency of C1 inhibitor (C1-INH) resulting in unpredictable, acute swelling attacks at varied locations. Icatibant, a selective bradikinin B2 receptor antagonist, is a novel treatment for acute attacks of HAE. The aim of the present study was to compare the efficacy beteween icatibant and fresh frozen plasma (FFP) in the acute attacks of HAE.