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Conjunctivitis: 57 Increased Frequency of CD4+ CCR4+ CCR9+ Cells in Patients With Allergic Conjunctivitis

机译:结膜炎:变应性结膜炎患者CD4 + CCR4 + CCR9 +细胞的频率增加57%

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摘要

BackgroundAllergic conjunctivitis is one of the most common diseases affecting the ocular surface, it has been suggested that T CD4+ cells regulate immune response in allergic diseases such as asthma and rhinitis, in a predominant Th2 response. In animal models, it has been observed a selective migration of CD4+ T cells to conjunctiva directed by chemokines; however molecules involved in CD4+ T cell migration in humans is unknown, thus it was the aim of this study.
机译:背景变应性结膜炎是影响眼表的最常见疾病之一,已经表明,T CD4 +细胞在主要的Th2反应中调节哮喘和鼻炎等变应性疾病的免疫反应。在动物模型中,已经观察到CD4 + T细胞选择性迁移到趋化因子引导的结膜中。然而,涉及人类CD4 + T细胞迁移的分子尚不清楚,因此这是本研究的目的。

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