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Follicular bronchiolitis: a rare disease in children

机译:滤泡性毛细支气管炎:小儿罕见病

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摘要

Follicular bronchiolitis (FB) is a benign progressive lung disease. It is characterized with lymphoplasmocellular infiltration and hyperplastic follicles in the peribronchial areas in the small airways. Follicular bronchiolitis should be considered in cases where chronic cough, recurrent upper respiratory tract infections and progressive dyspnea are observed in children. The diagnosis should be supported by lung biopsy. A 8-year old female patient presented to our hospital with complaints including continuing cough and wheezing. Bilateral extensive rales and rhonchi in the lungs were heard on auscultation and lung graphy revealed reticuloglandular appearance. Bilateral extensive septal thickennings, reticulonodular appearance, patchy bronchiectasis, bronchiolectasis and peribronchial thickennings were found on high-resolution thoracal computarized tomography. A diagnosis of follicular bronchiolitis was made as a result of lung biopsy. Improvement was observed in the complaints and findings of our patient after methylprednisolone treatment. This patient was presented to emphasize rare interstitial lung diseases should also be considered in children who present with a clinical picture of chronic bronchial obstruction and do not respond to standard treatment.
机译:滤泡性细支气管炎(FB)是一种良性进行性肺部疾病。其特征是小气道支气管周围区域有淋巴浆细胞浸润和增生卵泡。在儿童中观察到慢性咳嗽,反复出现的上呼吸道感染和进行性呼吸困难的情况下,应考虑滤泡性毛细支气管炎。诊断应辅以肺活检。一名8岁的女病人因持续咳嗽和喘息而到我们医院就诊。听诊时听到双侧肺部广泛的罗音和肺炎,肺部显露网状land状。在高分辨率的胸部计算机断层扫描中发现双侧广泛性间隔增厚,网状结节状外观,斑块性支气管扩张,支气管扩张和支气管周增厚。肺活检诊断为滤泡性毛细支气管炎。甲基泼尼松龙治疗后,患者的主诉和发现均得到改善。该患者的出现是为了强调那些患有慢性支气管阻塞且对标准治疗无反应的儿童,也应考虑罕见的间质性肺疾病。

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