Low serum zinc levels predict presence of depression symptoms but not overall disease outcome regardless of ATG16L1 genotype in Crohn’s disease patients

摘要

Background:Zinc deficiency (ZD) in Crohn’s disease (CD) is considered a frequent finding and may exacerbate CD activity. ZD is associated with depression in non-CD patients. We aimed to assess the prevalence of ZD in CD patients in clinical remission, its association with mood disturbances and to analyze a potential impact on future disease course.