首页> 美国卫生研究院文献>Journal of Visualized Experiments : JoVE >Prescribed 3-D Direct Writing of Suspended Micron/Sub-micron Scale Fiber Structures via a Robotic Dispensing System
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Prescribed 3-D Direct Writing of Suspended Micron/Sub-micron Scale Fiber Structures via a Robotic Dispensing System

机译:通过机械手分配系统对悬浮的微米级/亚微米级纤维结构进行规定的3D直接写入

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摘要

A 3-axis dispensing system is utilized to control the initiating and terminating fiber positions and trajectory via the dispensing software. The polymer fiber length and orientation is defined by the spatial positioning of the dispensing system 3-axis stages. The fiber diameter is defined by the prescribed dispense time of the dispensing system valve, the feed rate (the speed at which the stage traverses from an initiating to a terminating position), the gauge diameter of the dispensing tip, the viscosity and surface tension of the polymer solution, and the programmed drawing length. The stage feed rate affects the polymer solution’s evaporation rate and capillary breakup of the filaments. The dispensing system consists of a pneumatic valve controller, a droplet-dispensing valve and a dispensing tip. Characterization of the direct write process to determine the optimum combination of factors leads to repeatedly acquiring the desired range of fiber diameters. The advantage of this robotic dispensing system is the ease of obtaining a precise range of micron/sub-micron fibers onto a desired, programmed location via automated process control. Here, the discussed self-assembled micron/sub-micron scale 3D structures have been employed to fabricate suspended structures to create micron/sub-micron fluidic devices and bioengineered scaffolds.
机译:利用三轴分配系统通过分配软件控制纤维的起始和终止位置以及轨迹。聚合物纤维的长度和方向由分配系统3轴位移台的空间位置确定。纤维直径由分配系统阀的规定分配时间,进料速率(载物台从起始位置到终止位置的移动速度),分配尖端的直径,粘度和表面张力定义。聚合物溶液和编程的绘图长度。阶段进料速率会影响聚合物溶液的蒸发速率和长丝的毛细管破裂。分配系统包括一个气动阀控制器,一个液滴分配阀和一个分配尖端。确定直接因素的最佳组合的直接写入过程的特性导致重复获取所需的纤维直径范围。这种自动分配系统的优点是易于通过自动过程控制将精确范围的微米/亚微米纤维获得到所需的编程位置。在此,已讨论的自组装微米/亚微米级3D结构已用于制造悬浮结构,以创建微米/亚微米流体装置和生物工程支架。

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