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A Non-Invasive Medical Device for Parkinson’s Patients with Episodes of Freezing of Gait

机译:一种针对帕金森病患者的步态冻结发作的非侵入性医疗设备

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摘要

A critical symptom of Parkinson’s disease (PD) is the occurrence of Freezing of Gait (FOG), an episodic disorder that causes frequent falls and consequential injuries in PD patients. There are various auditory, visual, tactile, and other types of stimulation interventions that can be used to induce PD patients to escape FOG episodes. In this article, we describe a low cost wearable system for non-invasive gait monitoring and external delivery of superficial vibratory stimulation to the lower extremities triggered by FOG episodes. The intended purpose is to reduce the duration of the FOG episode, thus allowing prompt resumption of gait to prevent major injuries. The system, based on an Android mobile application, uses a tri-axial accelerometer device for gait data acquisition. Gathered data is processed via a discrete wavelet transform-based algorithm that precisely detects FOG episodes in real time. Detection activates external vibratory stimulation of the legs to reduce FOG time. The integration of detection and stimulation in one low cost device is the chief novel contribution of this work. We present analyses of sensitivity, specificity and effectiveness of the proposed system to validate its usefulness.
机译:帕金森氏病(PD)的一个严重症状是步态冻结(FOG),这是一种发作性疾病,会导致PD患者频繁跌倒并因此而受伤。有多种听觉,视觉,触觉和其他类型的刺激干预措施,可用于诱导PD患者逃避FOG发作。在本文中,我们描述了一种低成本的可穿戴系统,用于无创步态监测和由FOG发作触发的下肢表面振动刺激的外部传递。预期目的是减少FOG发作的持续时间,从而允许迅速恢复步态以防止重大伤害。该系统基于Android移动应用程序,使用三轴加速度计设备进行步态数据采集。收集的数据通过基于离散小波变换的算法进行处理,该算法可实时精确检测FOG发作。检测可激活腿部的外部振动刺激,以减少FOG时间。将检测和刺激集成在一个低成本的设备中是这项工作的主要新颖贡献。我们目前提出的系统的敏感性,特异性和有效性的分析,以验证其实用性。

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