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Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon

机译:癌症对胚胎学的影响与变异对遗传学的关系:癌症的假说作为胚胎学现象

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摘要

Despite numerous advances in cell biology, genetics, and developmental biology, cancer origin has been attributed to genetic mechanisms primarily involving mutations. Embryologists have expressed timidly cancer embryological origin with little success in leveraging the discussion that cancer could involve a set of conventional cellular processes used to build the embryo during morphogenesis. Thus, this “cancer process” allows the harmonious and coherent construction of the embryo structural base, and its implementation as the embryonic process involves joint regulation of differentiation, proliferation, cell invasion, and migration, enabling the human being recreation of every generation. On the other hand, “cancer disease” is the representation of an abnormal state of the cell that might happen in the stem cells of an adult person, in which the mechanism for joint gene regulating of differentiation, proliferation, cell invasion, and migration could be reactivated in an entirely inappropriate context.
机译:尽管细胞生物学,遗传学和发育生物学取得了许多进步,但癌症起源仍归因于主要涉及突变的遗传机制。胚胎学家胆怯地表达了癌症的胚胎起源,但在利用有关癌症可能涉及用于形态形成过程中构建胚胎的一系列常规细胞过程的讨论中,几乎没有成功。因此,这种“癌变过程”可以和谐而连贯地构建胚胎的结构基础,并且其作为胚胎过程的实施涉及分化,增殖,细胞侵袭和迁移的共同调节,从而使每一代人都能娱乐。另一方面,“癌症疾病”是成年人干细胞中可能发生的细胞异常状态的一种表现,在这种状态中,联合基因调控分化,增殖,细胞侵袭和迁移的机制可以在完全不合适的情况下重新激活。

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