Intramedullary nailing of femoral shaft fractures in polytraumatized patients. a longitudinal prospective and observational study of the procedure-related impact on cardiopulmonary- and inflammatory responses

摘要

BackgroundEarly intramedullary nailing (IMN) of long bone fractures in severely injured patients has been evaluated as beneficial, but has also been associated with increased inflammation, multi organ failure (MOF) and morbidity. This study was initiated to evaluate the impact of primary femoral IMN on coagulation-, fibrinolysis-, inflammatory- and cardiopulmonary responses in polytraumatized patients.