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For survival the emergence of oligoclonal bands after multiple myeloma treatment is less important than achieving complete remission

机译:为了生存多发性骨髓瘤治疗后出现寡克隆带并不比完全缓解重要

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摘要

BackgroundThe emergence of oligoclonal bands, proteins differing from those originally identified at diagnosis, has been reported in multiple myeloma patients after high-dose chemotherapy followed by autologous stem cell transplantation and after successful conventional chemotherapy. The clinical relevance of oligoclonal bands remains unclear, but their emergence has been associated with better prognosis. The aim of the present study was to determine the prevalence, clinical characteristics and prognostic impact of the presence of oligoclonal bands in multiple myeloma patients.
机译:背景在多剂量骨髓瘤患者中,高剂量化疗,自体干细胞移植后以及成功的常规化疗后,已经报道了寡克隆条带的出现,这种蛋白不同于诊断时最初鉴定的蛋白。寡克隆带的临床相关性尚不清楚,但它们的出现与更好的预后相关。本研究的目的是确定多发性骨髓瘤患者中存在寡克隆带的患病率,临床特征和预后影响。

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