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Adult type granulosa cell tumor in adult testis: report of a case and review of the literature

机译:成人睾丸中的成人型颗粒细胞瘤:一例报告并文献复习

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摘要

Granulosa cell tumors can be classified into juvenile and adult types and more commonly occur in ovaries. Adult testicular granulosa cell tumors are extremely rare and only 29 cases of adult type have previously been reported. We report here a 28-year old Caucasian man with a left testicular adult type granulosa cell tumor. The tumor measured 2.6×2.6×2.5 cm and was mitotically active (10/10 HPF). Immunohistochemical stains showed the tumor diffusely positive for inhibin and vimentin, and negative for epithelial membrane antigen, cytokeratins, synaptophysin, HMB-45, OCT-4, placental-like alkaline phosphatase and lymphoid markers. The reported granulosa cell tumors in adult testis were briefly reviewed.
机译:颗粒细胞瘤可分为少年型和成年型,多见于卵巢。成人睾丸颗粒细胞瘤极为罕见,以前仅报道过29例成人类型的病例。我们在这里报告一个28岁的白人男子,左睾丸成年型颗粒细胞瘤。肿瘤尺寸为2.6×2.6×2.5 cm,有丝分裂活跃(10/10 HPF)。免疫组织化学染色显示,肿瘤对抑制素和波形蛋白呈弥漫性阳性,而对上皮膜抗原,细胞角蛋白,突触素,HMB-45,OCT-4,胎盘样碱性磷酸酶和淋巴标记物呈阴性。简要回顾了成人睾丸中报告的颗粒细胞瘤。

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