Acute disseminated encephalomyelitis with peripheral nervous system involvement in an adult following measles: a case report and review of literature

摘要

Acute disseminated encephalomyelitis (ADEM) is an immune-mediated inflammatory disorder of the CNS usually precipitated by a viral infection or vaccination. Children are preferentially affected, and post-measles is most commonly, the incidence is about 1:1000. In the absence of specific biologic markers, the diagnosis of ADEM is still based on the clinical and neuroimaging features. ADEM is a rare disease in adults, to our knowledge, this is the first case report about adult ADEM following measles, and there was only few cases have been reported about ADEM with peripheral nervous system (PNS) involvement. Herein we report the case of a 22-year-old woman who was diagnosed ADEM with PNS injury after measles. After the administration of intravenous immunoglobulin (IVIG) and Steroid, the patient came to clinically recovery 7 weeks from symptom onset.