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3D Multi-Echo Dixon technique for simultaneous assessment of liver steatosis and iron overload in patients with chronic liver diseases: a feasibility study

机译:3D Multi-Echo Dixon技术同时评估慢性肝病患者肝脂肪变性和铁超负荷的可行性研究

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摘要

BackgroundPatients with chronic liver diseases (CLDs) often suffer from lipidosis or siderosis. Proton density fat fraction (PDFF) and R2* can be used as quantitative parameters to assess the fat/iron content of the liver. The aim of this study was to evaluate the influence of liver fibrosis and inflammation on the 3D Multi-echo Dixon (3D ME Dixon) parameters (MRI-PDFF and R2*) in patients with CLDs and to determine the feasibility of 3D ME Dixon technique for the simultaneous assessment of liver steatosis and iron overload using histopathologic findings as the reference standard.
机译:背景患有慢性肝病(CLD)的患者通常患有脂质过多或铁屑病。质子密度脂肪分数(PDFF)和R2 *可用作评估肝脏脂肪/铁含量的定量参数。这项研究的目的是评估肝纤维化和炎症对CLD患者3D多回波Dixon(3D ME Dixon)参数(MRI-PDFF和R2 *)的影响,并确定3D ME Dixon技术的可行性以组织病理学结果为参考标准同时评估肝脂肪变性和铁超负荷。

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