Peer Reviewed: Optimized Probability Sampling of Study Sites to Improve Generalizability in a Multisite Intervention Trial

摘要

IntroductionStudies of type 2 translation, the adaption of evidence-based interventions to real-world settings, should include representative study sites and staff to improve external validity. Sites for such studies are, however, often selected by convenience sampling, which limits generalizability. We used an optimized probability sampling protocol to select an unbiased, representative sample of study sites to prepare for a randomized trial of a weight loss intervention.