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Chronic tophaceous gout with unusual large tophi: case report

机译:慢性痛风性痛风伴大口疮:病例报告

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摘要

Gout is a metabolic disease, which is characterized by acute or chronic arthritis, and deposition of monosodium urate crystals in joint, bones, soft tissues, and kidneys. But large tophi are unusual in chronic gout. We report the case of a 67-year-oldArabman presenting chronic tophaceous gout with unusual large tophi involving multiple joints: hands, feet, elbows, and knees. Laboratory workup revealed elevated serum uric acid (96 mg/l, normal: 20-74 mg/l), with normal renal function test. In untreated patients, chronic tophaceous gout may develop, which is characterized by chronic destructive polyarticular involvement and tophi. The treatment consists to decrease serum uric acid level which eventually allows the regression of tophi.
机译:痛风是一种代谢性疾病,其特征是急性或慢性关节炎以及尿酸单钠晶体在关节,骨骼,软组织和肾脏中的沉积。但是大的痛风石在慢性痛风中并不常见。我们报告了一个67岁的阿拉伯人的病例,该人表现出慢性痛风性痛风,并伴有异常多发的大痛风石,涉及多个关节:手,脚,肘和膝盖。实验室检查发现血清尿酸升高(96 mg / l,正常:20-74 mg / l),肾功能检查正常。在未经治疗的患者中,可能会发生慢性趾状痛风,其特征是慢性破坏性多关节受累和痛风石。该治疗包括降低血清尿酸水平,这最终使痛风石消退。

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