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Combined treatment with minodronate and vitamin C increases bone mineral density and strength in vitamin C-deficient rats

机译：米诺膦酸盐和维生素C的联合治疗可增加缺乏维生素C的大鼠的骨矿物质密度和强度

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ObjectivesReduced bone quality caused by vitamin C deficiency in older persons may lead to incidental fragility fractures during bisphosphonate treatment, although bisphosphonate increases bone mineral density (BMD). This study aimed to evaluate the effects of minodronate and ascorbic acid (Aa) on BMD, bone quality, and bone strength in Aa-deficient osteogenic disorder Shionogi (ODS) rats.

机译：目的尽管双膦酸盐可增加骨矿物质密度（BMD），但老年人因维生素C缺乏引起的骨骼质量下降可能导致双膦酸盐治疗期间偶发的脆性骨折。这项研究旨在评估minodronate和抗坏血酸（Aa）对Aa缺乏成骨性疾病Shionogi（ODS）大鼠的BMD，骨质量和骨强度的影响。

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期刊名称 Osteoporosis and Sarcopenia
作者
Toyohito Segawa; Naohisa Miyakoshi; Yuji Kasukawa; Hiroshi Aonuma; Hiroyuki Tsuchie; Yoichi Shimada;
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作者单位

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年(卷),期 2016(2),1
年度 2016
页码 30–37
总页数 8
原文格式 PDF
正文语种
中图分类外科学 ;
关键词
Bone mineral density Bone strength Minodronate Vitamin C;

机译：骨矿物质密度;骨强度;米诺膦酸盐;维生素C;

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专利

1. Combined treatment with minodronate and vitamin C increases bone mineral density and strength in vitamin C-deficient rats [J] . Toyohito Segawa, Naohisa Miyakoshi, Yuji Kasukawa, Osteoporosis and Sarcopenia . 2016 ,第1期

机译：米诺膦酸盐和维生素C的联合治疗可增加缺乏维生素C的大鼠的骨矿物质密度和强度
2. Impact of vitamin C on teriparatide treatment in the improvement of bone mineral density, strength, and quality in vitamin C-deficient rats [J] . Miyakoshi Naohisa, Fujii Masashi, Kasukawa Yuji, Journal of bone and mineral metabolism . 2019 ,第3期

机译：维生素C对维生素C缺乏大鼠骨密度，强度和质量改善术后萜状碱处理的影响
3. Vitamin K supplement along with vitamin D and calcium reduced serum concentration of undercarboxylated osteocalcin while increasing bone mineral density in Korean postmenopausal women over sixty-years-old. [J] . Je SH, Joo NS, Choi BH, Journal of Korean medical science . 2011 ,第8期

机译：维生素K补充剂与维生素D和钙一起降低了60岁以上的韩国绝经后妇女的血清羧化骨钙素浓度，同时增加了骨矿物质密度。
4. Association of Vitamin D Receptor Gene Polymorphism and Bone Mineral Density: An Analysis by Possibility Theory [C] . Shih-Chuan Cheng, D. S. Malik, John N. Mordeson, World Multiconference on Systemics, Cybernetics and Informatics and 5th International Conference on Information Systems Analysis and Synthesis Vol.8: Concepts and applications of Systemics, Cybernetics and Informatics, Jul 31-Aug 4, 1999, Orlando, Flor . 1999

机译：维生素D受体基因多态性与骨矿物质密度的关联：可能性理论分析
5. The association between serum vitamin D status, bone mineral density, and forced expiratory volume in 1 second in pediatric cystic fibrosis patients [D] . Brantley, Caroline. 2016

机译：小儿囊性纤维化患者血清维生素D状况，骨矿物质密度与1秒钟呼气量之间的关系
6. The effects of minodronate and activated vitamin D on bone mineral density and muscle mass in postmenopausal women with osteoporosis [O] . Kazuki Fujimoto, Kazuhide Inage, Toru Toyoguchi, 2018

机译：米诺膦酸盐和活性维生素D对绝经后骨质疏松妇女骨矿物质密度和肌肉质量的影响
7. Combined treatment with minodronate and vitamin C increases bone mineral density and strength in vitamin C-deficient rats [O] . Segawa Toyohito, Miyakoshi Naohisa, Kasukawa Yuji, 2016

机译：米诺膦酸盐和维生素C的联合治疗可增加缺乏维生素C的大鼠的骨矿物质密度和强度

Combined treatment with minodronate and vitamin C increases bone mineral density and strength in vitamin C-deficient rats

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