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The Emerging Role of The Eosinophil and Its Measurement in Chronic Cough

机译:嗜酸性粒细胞的新兴作用及其在慢性咳嗽中的测定

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摘要

Although the aetiology of chronic cough in guidelines is clearly stated as asthma and related syndromes, gastro-oesophageal reflux disease (GORD), and upper airways disease, the inflammatory mechanisms underlying these conditions differ. Recent studies on asthma have increasingly focused on its molecular phenotypes instead of clinical characteristics. Here, we proposed the hypothesis that divides cough into two groups; the eosinophilic and neutrophilic. This division will enhance our ability to recognise the type of airway inflammation which, as a consequence will lead us to more targeted and personalized treatment approaches.
机译:尽管指南中明确指出慢性咳嗽的病因是哮喘和相关综合症,胃食管反流病(GORD)和上呼吸道疾病,但这些症状的炎症机制不同。最近关于哮喘的研究越来越关注其分子表型而不是临床特征。在这里,我们提出了将咳嗽分为两组的假说。嗜酸性和嗜中性的。这种区分将增强我们识别气道炎症类型的能力,因此将导致我们采用更具针对性和个性化的治疗方法。

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