Glycolysis in Patients with Age-Related Macular Degeneration

机译：与年龄相关的黄斑变性患者的糖酵解

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Purpose: Retinal adenosine triphosphate is mainly produced via glycolysis, so inhibition of glycolysis may promote the onset and progression of age-related macular degeneration (AMD). When glycolysis is inhibited, pyruvate is metabolized by lactic acid fermentation instead of entering the mitochondrial tricarboxylic acid (TCA) cycle. We measured urinary pyruvate and lactate levels in patients with AMD.

机译：目的：视网膜三磷酸腺苷主要通过糖酵解产生，因此抑制糖酵解可能会促进年龄相关性黄斑变性（AMD）的发作和发展。当糖酵解被抑制时，丙酮酸通过乳酸发酵被代谢，而不是进入线粒体三羧酸（TCA）循环。我们测量了AMD患者的尿中丙酮酸和乳酸水平。

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期刊名称 The Open Ophthalmology Journal
作者
Kanako Yokosako; Tatsuya Mimura; Hideharu Funatsu; Hidetaka Noma; Mari Goto; Yuko Kamei; Aki Kondo; Masao Matsubara;
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作者单位

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年(卷),期 2014(8),-1
年度 2014
页码 39–47
总页数 9
原文格式 PDF
正文语种
中图分类眼科学;
关键词
Age-related macular degeneration glycolysis ketone body lactate pyruvate.;

机译：与年龄有关的黄斑变性;糖酵解;酮体;乳酸;丙酮酸。;

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专利

1. Glycolysis in Patients with Age-Related Macular Degeneration [J] . Revision Received Date: The Open Ophthalmology Journal . 2014,第1期

机译：与年龄相关的黄斑变性患者的糖酵解
2. Association of Visit Adherence and Visual Acuity in Patients With Neovascular Age-Related Macular Degeneration Secondary Analysis of the Comparison of Age-Related Macular Degeneration Treatment Trial [J] . Ramakrishnan Meera S., Yu Yinxi, VanderBeek Brian L. JAMA ophthalmology . 2020,第3期

机译：新生心血管年龄相关黄斑患者患者的访问粘附和视力协会与年龄相关性黄斑治疗试验比较的患者
3. Development of typical age-related macular degeneration and polypoidal choroidal vasculopathy in fellow eyes of Japanese patients with exudative age-related macular degeneration. [J] . Ueta T, Iriyama A, Francis J, American Journal of Ophthalmology: The International Journal of Ophthalmology . 2008,第1期

机译：日本渗出性年龄相关性黄斑变性患者同龄眼中典型的年龄相关性黄斑变性和息肉样脉络膜血管病的发展。
4. An Augmented Reality Assistant to Support Button Selection for Patients with Age-related Macular Degeneration [C] . Patrik Gonçalves, Jason Orlosky, Tonja-Katrin Machulla IEEE Conference on Virtual Reality and 3D User Interfaces Abstracts and Workshops . 2020

机译：增强现实助手，支持年龄相关性黄斑变性患者的按钮选择
5. Characterizing the Healthcare Resource Utilization and Costs By Disease Severity Among Patients with Geographic Atrophy Secondary to Age-Related Macular Degeneration [D] . Kim, Ashley. 2019

机译：在与年龄相关黄斑变性的地理萎缩患者中，通过疾病严重程度表征医疗资源利用率和成本
6. Comparing vision and macular thickness in neovascular age-related macular degeneration diabetic macular oedema and retinal vein occlusion patients treated with intravitreal antivascular endothelial growth factor injections in clinical practice [O] . Rajya L Gurung, Liesel M FitzGerald, Bennet J McComish, 2021

机译：在临床实践中对新生血管年龄相关性黄斑糖尿病黄斑水肿和视网膜静脉阻塞患者进行了视觉和黄斑厚度
7. Avaliação da função macular por eletrorretinografia focal e por angiofluoresceinografia em pacientes com degeneração macular relacionada à idade neovascular submetidos à terapia fotodinâmica com verteporfina Evaluation of the macular function by focal electroretinography and by fluorescein angiography in patients with neovascular age-related macular degeneration submitted to verteporfin photodynamic therapy [O] . Akiyoshi Oshima, Adriana Berezovsky, Solange Rios Salomão, 2009

机译：新生血管性年龄相关性黄斑变性患者使用维替泊芬光动力疗法评价黄斑功能的局灶性视网膜电图和血管荧光检查评估新生血管性年龄相关性黄斑变性患者的局灶性视网膜电图和荧光血管造影评价黄斑功能治疗

Glycolysis in Patients with Age-Related Macular Degeneration

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