Crystal structures of two thia­zolidinone derivatives bearing a tri­chloro­methyl substituent at the 2-position

摘要

The title compounds 2-tri­chloro­methyl-3-phenyl-1,3-thia­zolidin-4-one (C10H8Cl3NOS), >1 and 3-(4-chloro­phen­yl)-2-tri­chloro­methyl-1,3-thia­zolidin-4-one (C10H7Cl4NOS) >2, are structurally related with one atom substitution difference in the para position of the benzene ring. In both structures, the thia­zolidinone ring adopts an envelope conformation with the S atom as the flap. The dihedral angles between the rings [48.72 (11) in >1 and 48.42 (9)° in >2] are very similar and the mol­ecules are almost superimposable. In both crystal structures, C—H⋯O ‘head-to-tail’ inter­actions between the chiral carbon atoms and the thia­zolidinone oxygen atoms result in infinite monochiral chains along the direction of the shortest unit-cell parameter, namely a in >1 and b in >2. C—H⋯π inter­actions between the thia­zolidinone carbon atom at the 4-position and the phenyl ring of the neighboring enanti­omer also help to stabilize the packing in each case, although the crystals are not isostructural.