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Influence of companion diagnostics on efficacy and safety of targeted anti-cancer drugs: systematic review and meta-analyses

机译：伴随诊断对靶向抗癌药疗效和安全性的影响：系统评价和荟萃分析

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BackgroundCompanion diagnostics aim to identify patients that will respond to targeted therapies, therefore increasing the clinical efficacy of such drugs. Less is known about their influence on safety and tolerability of targeted anti-cancer agents.

机译：背景技术伴随诊断法旨在鉴定对靶向疗法有反应的患者，从而提高此类药物的临床疗效。关于它们对靶向抗癌药的安全性和耐受性的影响知之甚少。

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期刊名称 Oncotarget
作者
Alberto Ocana; Josee-Lyne Ethier; Laura Díez-González; Verónica Corrales-Sánchez; Amirrtha Srikanthan; María J. Gascón-Escribano; Arnoud J. Templeton; Francisco Vera-Badillo; Bostjan Seruga; Saroj Niraula; Atanasio Pandiella; Eitan Amir;
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作者单位

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年(卷),期 2015(6),37
年度 2015
页码 39538–39549
总页数 12
原文格式 PDF
正文语种
中图分类肿瘤学;细胞生物学;
关键词
cancer drugs companion diagnostics efficacy trial design;

机译：癌症药物;伴随诊断;功效;试验设计;

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机译：伴随诊断对靶向抗癌药疗效和安全性的影响：系统评价和荟萃分析

Influence of companion diagnostics on efficacy and safety of targeted anti-cancer drugs: systematic review and meta-analyses

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