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SIK1-LNC represses the proliferative migrative and invasive abilities of lung cancer cells

机译：SIK1-LNC抑制肺癌细胞的增殖迁移和侵袭能力

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BackgroundDiscussions regarding the correlations between long non-coding RNAs (lncRNAs) and cancers have dominated research in recent years. SIK1-LNC, a type of lncRNA and adjacent to salt-inducible kinases 1 (SIK1), has been found aberrantly expressed in lung cancer. However, its functional role in lung cancer remains largely unknown.

机译：背景技术近年来，关于长非编码RNA（lncRNA）与癌症之间相关性的讨论主导了研究。 SIK1-LNC是lncRNA的一种，与盐诱导性激酶1（SIK1）相邻，已在肺癌中异常表达。但是，其在肺癌中的功能作用仍然未知。

著录项

期刊名称 OncoTargets and therapy
作者
Liu Yang; Nianlin Xie; Jingyu Huang; Hu Huang; Shaogan Xu; Zhigang Wang; Jun Cai;
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作者单位

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年(卷),期 2018(11),-1
年度 2018
页码 4197–4206
总页数 10
原文格式 PDF
正文语种
中图分类应用微生物学;肿瘤学;
关键词
lung cancer SIK1-LNC SIK1 proliferation invasion metastasis;

机译：肺癌;SIK1-LNC;SIK1;增殖;侵袭;转移;

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专利

1. SIK1-LNC represses the proliferative, migrative, and invasive abilities of lung cancer cells [J] . Liu Yang, Nianlin Xie, Jingyu Huang, OncoTargets and therapy . 2018,第4期

机译：SIK1-LNC抑制肺癌细胞的增殖，迁移和侵袭能力
2. hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression [J] . Michael G. Edwards, Katherine Vandervest, John Arcaroli, Biology Open . 2013,第7期

机译：hsa-miR29b（非经典Wnt信号的关键下游靶标）通过靶向MDM2表达在非小细胞肺癌细胞中发挥抗增殖作用hsa-miR29b（非经典Wnt信号的关键下游靶标）通过靶向MDM2表达在非小细胞肺癌细胞中的抗增殖作用hsa-miR29b（非经典Wnt信号的关键下游靶点）通过靶向MDM2表达在非小细胞肺癌细胞中发挥抗增殖作用
3. MiR-145 and miR-203 represses TGF-beta-induced epithelial-mesenchymal transition and invasion by inhibiting SMAD3 in non-small cell lung cancer cells [J] . Hu Haibo, Xu Zhenlei, Li Chang, Lung cancer: Journal of the International Association for the Study of Lung Cancer . 2016,第Null期

机译：MiR-145和miR-203通过抑制非小细胞肺癌细胞中的SMAD3抑制TGF-beta诱导的上皮-间质转化和侵袭
4. The Proliferative Inhibition and Apoptotic Mechanism of Saikosaponin D in Human Non-Small Cell Lung Cancer A549 Cells [C] . Jiang Dong, Yang Ru-song, Zheng Shi-ying, Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009 . 2009

机译：皂苷D在人非小细胞肺癌A549细胞中的增殖抑制及其凋亡机制
5. The effect of amphiregulin and NF-kappaB/IL-1 autoinductive loops on the proliferative, invasive, and migratory properties of human breast cancer cells. [D] . Willmarth, Nicole Erickson. 2007

机译：两性调节蛋白和NF-κB/ IL-1自诱导环对人乳腺癌细胞增殖，侵袭和迁移特性的影响。
6. The expression of Nectin-4 on the surface of ovarian cancer cells alters their ability to adhere migrate aggregate and proliferate [O] . Kristin L.M. Boylan, Petra C. Buchanan, Rory D. Manion, 2017

机译：Nectin-4在卵巢癌细胞表面的表达改变了它们粘附迁移聚集和增殖的能力
7. SIK1-LNC represses the proliferative, migrative, and invasive abilities of lung cancer cells [O] . Liu Yang, Nianlin Xie, Jingyu Huang, 2018

机译：Sik1-LNC压制肺癌细胞的增殖性，迁移和侵入性能力

SIK1-LNC represses the proliferative migrative and invasive abilities of lung cancer cells

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