Immunohistochemical expression of hormone receptors Ki-67 endoglin (CD105) claudins 3 and 4 MMP-2 and -9 in endometrial polyps and endometrial cancer type I

摘要

ObjectiveThe aim of this study was to investigate the malignant potential of endometrial polyps (EP) by assessing the immunoexpressions of both estrogen receptor (ER) and progesterone receptor (PR), Ki-67 cell proliferation index, neovascularization network (endoglin – CD105), cellular adhesion molecules (claudins 3 and 4), and extracellular matrix proteins (MMP-2 and -9) in both EP and endometrioid adenocarcinoma (type I) in comparison with the normal endometrium.