Direct Proof of the 5′ to 3′ Transcriptional Jump During Reverse Transcription of the Avian Retrovirus Genome by DNA Sequencing

摘要

DNA sequence analysis of avian sarcoma virus in vitro-synthesized complementary DNA and in vivo-synthesized, molecularly cloned viral DNA provides unequivocal proof that only one copy of the terminally redundant viral RNA sequence is copied during reverse transcription.