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A Phase I/II Study of the Investigational Drug Alisertib in Combination With Abiraterone and Prednisone for Patients With Metastatic Castration-Resistant Prostate Cancer Progressing on Abiraterone

机译：I / II期研究药物Alisertib联合阿比特龙和强的松治疗Abiraterone进展性去势抵抗前列腺癌的患者的I / II期研究

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Lessons Learned class="unordered" style="list-style-type:disc">Patients with metastatic castration-resistant prostate cancer did not tolerate the combination of alisertib with abiraterone and prednisone.There was no clear signal indicating that adding alisertib might be beneficial for those patients progressing on abiraterone.

机译：经验教训 class =“ unordered” style =“ list-style-type：disc”> <！-list-behavior = unordered prefix-word = mark-type = disc max-label-size = 0-> < li>患有转移性去势抵抗性前列腺癌的患者不能耐受alisertib与阿比特龙和泼尼松的组合。没有明确的信号表明添加alisertib可能对那些接受阿比特龙治疗的患者有益。 li>

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期刊名称 The Oncologist
作者
Jianqing Lin; Sheel A. Patel; Ashwin R. Sama; Jean H. Hoffman-Censits; Brooke Kennedy; Deborah Kilpatrick; Zhong Ye; Hushan Yang; Zhaomei Mu; Benjamin Leiby; Nancy Lewis; Massimo Cristofanilli; William Kevin Kelly;
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年(卷),期 2016(21),11
年度 2016
页码 1296–1297e
总页数 7
原文格式 PDF
正文语种
中图分类肿瘤学;
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1. A Phase I/II Study of the Investigational Drug Alisertib in Combination With Abiraterone and Prednisone for Patients With Metastatic Castration-Resistant Prostate Cancer Progressing on Abiraterone [J] . Lin Jianqing, Patel Sheel A., Sama Ashwin R., The oncologist . 2016,第11期

机译：I / II期研究药物Alisertib联合阿比特龙和强的松治疗Abiraterone进展性去势抵抗前列腺癌的患者的I / II期研究
2. A Phase I/II Study of the Investigational Drug Alisertib in Combination With Abiraterone and Prednisone for Patients With Metastatic Castration-Resistant Prostate Cancer Progressing on Abiraterone [J] . Jianqing Lin, Sheel A. Patel, Ashwin R. Sama, The oncologist . 2016,第11期

机译：I / II期研究药物Alisertib联合阿比特龙和强的松治疗Abiraterone进展性去势抵抗前列腺癌的患者的I / II期研究
3. Abiraterone acetate in combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer: U.S. food and drug administration drug approval summary [J] . KluetzP.G., NingY.-M., MaherV.E., Clinical cancer research: an official journal of the American Association for Cancer Research . 2013,第24期

机译：醋酸阿比特龙与泼尼松联用于治疗转移性去势抵抗性前列腺癌患者：美国食品药品监督管理局药品批准摘要
4. Metastatic Hormone-Sensitive and Castration-Resistant Prostate Cancer: A Decade of Progress and Ongoing Discoveries [C] . Leonel Hernez-Aya, Maha Hussain Genitourinary Cancers Symposium. . 2014

机译：转移激素敏感和阉割的前列腺癌：进步和持续发现的十年
5. Muscle Cross-Sectional Area Is Improved and Physical Funciton Is Maintained After Home-Based Exercise in Men with Metastatic Castration-Resistant Prostate Cancer Undergoing Androgen Deprivation Therapy [D] . Alzer, Mohamdod Saber. 2020

机译：改善肌横截面积，并且在具有转移阉割的前列腺癌接受雄激素剥夺治疗的男性中的男性锻炼之后，将物理静脉凝集维持
6. A randomized phase IIa study of quantified bone scan response in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with radium-223 dichloride alone or in combination with abiraterone acetate/prednisone or enzalutamide [O] . D.P. Petrylak, U.N. Vaishampayan, K.R. Patel, 2021

机译：含镭-223二氯化钠或与AbiraTerone醋酸盐/泼尼松或苯甲酸丁酰胺组合处理的转移阉割抗性前列腺癌（MCRPC）的量化骨扫描响应的随机相IIA研究
7. A randomized phase IIa study of quantified bone scan response in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with radium-223 dichloride alone or in combination with abiraterone acetate/prednisone or enzalutamide [O] . D.P. Petrylak, U.N. Vaishampayan, K.R. Patel, 2021

机译：含镭-223二氯化钠或与AbiraTerone醋酸盐/泼尼松或苯甲酸丁酰胺组合处理的转移阉割抗性前列腺癌（MCRPC）的量化骨扫描响应的随机相IIA研究

A Phase I/II Study of the Investigational Drug Alisertib in Combination With Abiraterone and Prednisone for Patients With Metastatic Castration-Resistant Prostate Cancer Progressing on Abiraterone

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