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Prognostic Impact of Phosphorylated HER-2 in HER-2+ Primary Breast Cancer

机译：磷酸化的HER-2对HER-2 +原发性乳腺癌的预后影响

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摘要

Purpose.Tyrosine 1248 is one of the autophosphorylation sites of human epidermal growth factor receptor (HER)-2. We determined the prognostic value of the expression level of tyrosine 1248–phosphorylated HER-2 (pHER-2) in patients with HER-2⁺ primary breast cancer using a reverse-phase protein array.

机译：目的：酪氨酸1248是人类表皮生长因子受体（HER）-2的自磷酸化位点之一。我们使用反相蛋白阵列测定了酪氨酸1248-磷酸化HER-2（pHER-2）表达水平对HER-2 ^{+ 原发性乳腺癌患者的预后价值。}

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期刊名称 The Oncologist
作者
Naoki Hayashi; Takayuki Iwamoto; Ana M. Gonzalez-Angulo; Jaime Ferrer-Lozano; Ana Lluch; Naoki Niikura; Chandra Bartholomeusz; Seigo Nakamura; Gabriel N. Hortobagyi; Naoto T. Ueno;
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作者单位

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年(卷),期 2011(16),7
年度 2011
页码 956–965
总页数 10
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Breast cancer HER-2 Reverse-phase protein array Metastases Phosphorylation;

机译：乳腺癌;HER-2;反相蛋白阵列;转移;磷酸化;

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专利

1. SUCI02选择性抑制HER-2/neu受体酪氨酸激酶磷酸化及其对HER-2/neu过表达乳腺癌细胞生长的影响 [J] . 朱孝峰, 刘宗潮, 谢冰芬, 癌症（英文版） . 2003,第008期
2. Prognostic impact of phosphorylated HER-2 in HER-2+ primary breast cancer. [J] . Hayashi N, Iwamoto T, Gonzalez Angulo AM, The oncologist . 2011,第7期

机译：磷酸化HER-2对HER-2 +原发性乳腺癌的预后影响。
3. Erratum to: Correlation between quantitative HER-2 protein expression and risk for brain metastases in HER-2+ advanced breast cancer patients receiving trastuzumab-containing therapy, (The Oncologist, (2012), 17, (26-35)) [J] . The oncologist . 2013,第6期

机译：勘误至：接受曲妥珠单抗治疗的HER-2 +晚期乳腺癌患者中HER-2定量蛋白表达与脑转移风险之间的相关性，（The Oncologist，（2012），17，（26-35））
4. Correlation Between Quantitative HER-2 Protein Expression and Risk for Brain Metastases in HER-2+ Advanced Breast Cancer Patients Receiving Trastuzumab-Containing Therapy [J] . Renata Duchnowska, Wojciech Biernat, Barbara Szostakiewicz, The oncologist . 2012,第1期

机译：HER-2 +晚期乳腺癌患者患者含曲妥珠单抗治疗的定量HER-2蛋白表达与脑转移风险的相关性
5. CLINICAL AND PROGNOSTIC SIGNIFICANCE OF PREOPERATIVE SERUM CA15-3,CEA AND TPS LEVELS IN PATIENTS WITH PRIMARY BREAST CANCER [C] . Yu-hong Zheng, Yan Chen, Ying-ying Lin 2011 Asia-Pacific Conference of tumor biology and medicine . 2011

机译：原发性乳腺癌患者术前血清CA15-3，CEA和TPS水平的临床和预后意义
6. Impact of HER-2/neu detection by fluorescence in situ hybridization (FISH) on trastuzumab therapy in the treatment of metastatic breast cancer. [D] . Subongkot, Suphat. 2003

机译：荧光原位杂交（FISH）检测HER-2 / neu对曲妥珠单抗治疗转移性乳腺癌的影响。
7. Correlation Between Quantitative HER-2 Protein Expression and Risk for Brain Metastases in HER-2+ Advanced Breast Cancer Patients Receiving Trastuzumab-Containing Therapy [O] . Renata Duchnowska, Wojciech Biernat, Barbara Szostakiewicz, 2013

机译：接受曲妥珠单抗治疗的HER-2 +晚期乳腺癌患者中HER-2定量蛋白表达与脑转移风险的相关性
8. Prognostic Impact of Phosphorylated HER-2 in HER-2+ Primary Breast Cancer [O] . Hayashi, Naoki, Iwamoto, Takayuki, González-Angulo, Ana María, 2011

机译：磷酸化的HER-2对HER-2 +原发性乳腺癌的预后影响

Prognostic Impact of Phosphorylated HER-2 in HER-2+ Primary Breast Cancer

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