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The Medicago Genome Initiative: a model legume database

机译:苜蓿基因组 倡议:豆科植物模型数据库

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摘要

The Medicago Genome Initiative (MGI) is a database of EST sequences of the model legume Medicago truncatula. The database is available to the public and has resulted from a collaborative research effort between the Samuel Roberts Noble Foundation and the National Center for Genome Resources to investigate the genome of M.truncatula. MGI is part of the greater integrated Medicago functional genomics program at the Noble Foundation (href="http://http://www.noble .org" data-ga-action="click_feat_suppl" ref="reftype=extlink&article-id=29836&issue-id=900&journal-id=4&FROM=Article%7CFront%20Matter&TO=External%7CLink%7CURI" target="_blank">http://www.noble .org), which is taking a global approach in studying the genetic and biochemical events associated with the growth, development and environmental interactions of this model legume. Our approach will include: large-scale EST sequencing, gene expression profiling, the generation of M.truncatula activation-tagged and promoter trap insertion mutants, high-throughput metabolic profiling, and proteome studies. These multidisciplinary information pools will be interfaced with one another to provide scientists with an integrated, holistic set of tools to address fundamental questions pertaining to legume biology. The public interface to the MGI database can be accessed at .
机译:Medicago Genome Initiative(MGI)是豆科植物Medicago truncatula模型的EST序列数据库。该数据库可供公众使用,该数据库是塞缪尔·罗伯茨·诺布尔基金会与国家基因组资源国家中心之间的一项合作研究成果,目的是研究特兰卡图拉山的基因组。 MGI是Noble Foundation(href =“ http:// http://www.noble”)更大的综合Medicago功能基因组计划的一部分 .org“ data-ga-action =” click_feat_suppl“ ref =” reftype = extlink&article-id = 29836&issue-id = 900&journal-id = 4&FROM = Article%7CFront%20Matter&TO = External%7CLink%7CURI“ target =” _ blank“> http ://www.noble .org ),该机构正在采用一种全球性方法来研究与该豆科植物的生长,发育和环境相互作用相关的遗传和生化事件,我们的方法将包括:大规模EST测序,基因表达谱分析,M.truncatula激活标记和启动子陷阱插入突变体的产生,高通量代谢谱分析和蛋白质组学研究,这些多学科的信息库将相互衔接,为科学家提供一个集成的整体集合解决与豆科生物学有关的基本问题的工具,MGI数据库的公共接口可以 可在访问。

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