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>P01.136 Safety and adverse event profile of tumor treating fields in elderly patients - a post-market surveillance analysis
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P01.136 Safety and adverse event profile of tumor treating fields in elderly patients - a post-market surveillance analysis
BackgroundTumor Treating Fields (TTFields) are an established modality for glioblastoma (GBM) treatment administered through the portable Optune system. The efficacy of Optune in newly diagnosed GBM was previously demonstrated in the EF-14 phase 3 trial (n=695). Optune plus temozolomide significantly improved survival in all patient subgroups compared to temozolomide alone, which included those patients ≥ 65 years of age (median OS: 17.1 vs 13.7 months). Here, we report post-marketing surveillance data from elderly patients treated with Optune.
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机译:背景肿瘤治疗场(TTFields)是通过便携式Optune系统进行胶质母细胞瘤(GBM)治疗的既定模式。先前在EF-14第3期试验(n = 695)中证明了Optune在新诊断的GBM中的功效。与单独使用替莫唑胺相比,Optune加替莫唑胺在所有患者亚组中均显着提高了生存率,其中包括≥65岁的患者(中位OS:17.1 vs 13.7个月)。在这里,我们报告了使用Optune治疗的老年患者的上市后监测数据。
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