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PATH-45. INTEGRATION OF MULTI-REGION (EPI)GENOMICS WITH MULTIMODALITY ADVANCED IMAGING HIGHLIGHTS GLIOMA INTRATUMORAL HETEROGENEITY

机译：路径45。多区域（EPI）基因组学与多模态先进的成像亮点的融合胶质瘤内异质性

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INTRODUCTIONIntratumoral (epi)genetic heterogeneity is recognized to be an important driver in glioma therapy resistance. A single biopsy is unlikely to represent the true spatial and temporal heterogeneity. Therefore, multiple sampling schemes guided by imaging are needed.

机译：引言瘤内（epi）遗传异质性是胶质瘤治疗耐药性的重要驱动因素。一次活检不可能代表真实的时空异质性。因此，需要以成像为指导的多种采样方案。

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期刊名称 Neuro-Oncology
作者
Niels Verburg; Kevin C Johnson; Floris P Barthel; Michael Taylor; Joseph Costello; Philip C de Witt Hamer; Pieter Wesseling; Roel Verhaak;
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作者单位

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年(卷),期 2017(19),Suppl 6
年度 2017
页码 vi181
总页数 1
原文格式 PDF
正文语种
中图分类神经病学;肿瘤学;
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专利

1. Intratumoral genomic heterogeneity in advanced head and neck cancer detected by comparative genomic hybridization. [J] . Gotte K, Tremmel SC, Popp S, Advances in oto-rhino-laryngology . 2005,第0期

机译：通过比较基因组杂交检测晚期头颈癌的肿瘤内基因组异质性。
2. T2-weighted images are superior to other MR image types for the determination of diffuse intrinsic pontine glioma intratumoral heterogeneity [J] . Harward Stephen, Farber S. Harrison, Malinzak Michael, Child's nervous system: ChNS : official journal of the International Society for Pediatric Neurosurgery . 2018,第3期

机译：T2加权图像优于其他MR图像类型，用于测定弥漫性固有型脊髓瘤肿瘤内异质性
3. Multimodal Imaging to Delineate Tumor Heterogeneity in Cerebral Gliomas [J] . Astrid Ellen Grams, Jens Gempt, Florian Ringel, Open Journal of Radiology . 2014,第2期

机译：多模式成像描绘脑胶质瘤的肿瘤异质性
4. MULTIMODAL OPTICAL IMAGING DATABASE FROM TUMOUR BRAIN HUMAN TISSUE: ENDOGENEOUS FLUORESCENCE FROM GLIOMAS, METASTASES AND CONTROL TISSUES [C] . Fanny Poulon, Ali Ibrahim, Marc Zanello, Multiphoton microscopy in the biomedical sciences XVII . 2017

机译：肿瘤脑组织的多模态光学成像数据库：来自胶质瘤，转移瘤和对照组织的内源性荧光
5. Evolution of low-grade glioma through intratumoral heterogeneity of the genome and epigenome. [D] . Mazor, Tali. 2016

机译：低级神经胶质瘤通过基因组和表观基因组的肿瘤内异质性进化。
6. ECOA-5. Integrative 3D spatial characterization of genomic and epigenomic intratumoral heterogeneity in glioblastoma [O] . Radhika Mathur, Qixuan Wang, Patrick Schupp, 2021

机译：ECOA-5。胶质母细胞瘤中基因组和表观脑肿瘤内异质性的整合3D空间特征
7. INTRATUMORAL HETEROGENEITY OF THE ACTIVITY OF PROTEIN KINASE MΖ AND PROTEIN KINASE C IOTA IN DIFFUSE GLIOMAS: ISOLATION OF CELL CLUSTERS, THEIR MOLECULAR CHARACTERIZATION AND ASSESSMENT OF STEM PROPERTIES [O] . P.V. Nikitin, M.V. Ryzhova, I.V. Zubova, 2020

机译：弥漫性胶质瘤中蛋白激酶Mζ和蛋白激酶C IOTA活性的肿瘤激酶C酶的肿瘤：细胞簇的分离，它们的分子表征及茎特性评估

PATH-45. INTEGRATION OF MULTI-REGION (EPI)GENOMICS WITH MULTIMODALITY ADVANCED IMAGING HIGHLIGHTS GLIOMA INTRATUMORAL HETEROGENEITY

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