Quantitative HER2 and p95HER2 levels in primary breast cancers and matched brain metastases

摘要

BackgroundPatients with advanced breast cancer positive for human epidermal growth factor receptor 2 (HER2) are at high risk for brain metastasis (BM). The prevalence and significance of expression of HER2 and its truncated form p95HER2 (p95) in BM is unknown.