Chemical Constituents of a Marine-Derived Endophytic Fungus Penicillium commune G2M

摘要

Cultivation of the endophytic fungus Penicillium commune, which was isolated from the semi-mangrove plant Hibiscus tiliaceus, afforded one new compound 1-O-(2,4-dihydroxy-6-methylbenzoyl)-glycerol (>1) along with thirteen known products, including 1-O-acetylglycerol (>2), N-acetyltryptophan (>3), 3-indolylacetic acid methyl ester (>4), 1-(2,4-dihydroxy-3,5-dimethylphenyl)ethanone (>5), 2-(2,5-dihydroxyphenyl)acetic acid (>6), (4R,5S)-5-hydroxyhexan-4-olide (>7), thymidine (>8), uracil (>9), thymine (>10), ergosterol (>11), β-sitosterol (>12), β-daucosterol (>13), and ergosta-7,22-dien-3β,5α,6β-triol (>14). The structures of these compounds were established by detailed NMR spectroscopic analysis, as well as by comparison with literature data or with authentic samples.