首页> 美国卫生研究院文献>Medical Science Monitor Basic Research >Rosmarinic Acid Analogue-11 Induces Apoptosis of Human Gastric Cancer SGC-7901 Cells via the Epidermal Growth Factor Receptor (EGFR)/Akt/Nuclear Factor kappa B (NF-κB) Pathway

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Rosmarinic Acid Analogue-11 Induces Apoptosis of Human Gastric Cancer SGC-7901 Cells via the Epidermal Growth Factor Receptor (EGFR)/Akt/Nuclear Factor kappa B (NF-κB) Pathway

机译：迷迭香酸类似物11通过表皮生长因子受体（EGFR）/ Akt /核因子κB（NF-κB）途径诱导人胃癌SGC-7901细胞凋亡

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BackgroundAccording to the latest statistics from the American Cancer Society, there will be 1.73 million cancer cases and more than 600 000 cancer deaths in the United States in 2018, among which there will be 26 240 new cases of gastric cancer and around 10 800 deaths arising from gastric cancer. The objective of this study was to use RAA-11 to intervene in SGC-7901 cells to understand its effects on cell proliferation and apoptosis, and to explore the apoptosis mechanism.

机译：背景根据美国癌症协会的最新统计数据，2018年美国将有173万例癌症病例和60万多例癌症死亡，其中将有26240例胃癌新病例和约10800例死亡来自胃癌。这项研究的目的是使用RAA-11干预SGC-7901细胞，以了解其对细胞增殖和凋亡的影响，并探讨其凋亡机制。

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期刊名称 Medical Science Monitor Basic Research
作者
Wanting Li; Qing Li; Liqun Wei; Xiaohang Pan; Daohang Huang; Jialiang Gan; Shuangyi Tang;
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作者单位

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年(卷),期 2019(25),-1
年度 2019
页码 63–75
总页数 13
原文格式 PDF
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中图分类
关键词
Apoptosis Cell Proliferation Genes erbB-1 NF-kappa B Proto-Oncogene Proteins c-akt Rosmarinus;

机译：凋亡;细胞增殖;基因;erbB-1;NF-κB;原癌基因蛋白c-akt;迷迭香;

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专利

1. Rosmarinic Acid Analogue-11 Induces Apoptosis of Human Gastric Cancer SGC-7901 Cells via the Epidermal Growth Factor Receptor (EGFR)/Akt/Nuclear Factor kappa B (NF-κB) Pathway [J] . Wanting Li, Qing Li, Liqun Wei, Medical Science Monitor Basic Research . 2019 ,第1期

机译：迷迭香酸类似物11通过表皮生长因子受体（EGFR）/ Akt /核因子κB（NF-κB）途径诱导人胃癌SGC-7901细胞凋亡
2. Down-Regulation of Human Epidermal Growth Factor Receptor 2eu Oncogene by Corosolic Acid Induces Cell Cycle Arrest and Apoptosis in NCI-N87 Human Gastric Cancer Cells [J] . Myung Sun Lee, Eun Young Cha, Phuong Thien Thuong, Biological & pharmaceutical bulletin . 2010 ,第6期

机译：胆固醇对人表皮生长因子受体2 / neu癌基因的下调诱导NCI-N87人胃癌细胞的细胞周期阻滞和凋亡
3. Betulinic Acid-Mediated Apoptosis in Human Prostate Cancer Cells Involves p53 and Nuclear Factor-Kappa B (NF-κB) Pathways [J] . Eswar Shankar, Ailin Zhang, Daniel Franco, Molecules . 2017 ,第2期

机译：桦木酸介导的人类前列腺癌细胞凋亡涉及p53和核因子-κB（NF-κB）途径
4. Targeting of Epidermal Growth Factor Receptor (EGFR)-positive pancreatic cancer cell lines with cetuximab-conjugated near-infrared silver sulphide quantum dots [C] . Peter L. Labib, Elnaz Yaghini, Mahshid Hashemkhani, International Photodynamic Association World Congress;Society of Photo-Optical Instrumentation Engineers;International Photodynamic Association . 2019

机译：西妥昔单抗缀合的近红外硫化银量子点靶向表皮生长因子受体（EGFR）阳性胰腺癌细胞系
5. The prognostic potential of the epidermal growth factor receptor and nuclear factor kappa B pathways and associated therapeutic strategies in patients with squamous cell carcinoma of the head and neck. [D] . Wirth, Pamela Susan. 2010

机译：表皮生长因子受体和核因子κB通路对头颈部鳞状细胞癌患者的预后潜力及相关治疗策略。
6. Positive Cross-Talk Between CXC Chemokine Receptor 4 (CXCR4) and Epidermal Growth Factor Receptor (EGFR) Promotes Gastric Cancer Metastasis via the Nuclear Factor kappa B (NF-κB)-Dependent Pathway [O] . Yu Cheng, Xiaofang Che, Simeng Zhang, 2020

机译：CXC趋化因子受体4（CXCR4）和表皮生长因子受体（EGFR）之间的阳性串扰通过核因子Kappa B（NF-κB） - 依赖性途径促进胃癌转移
7. Rosmarinic Acid Analogue-11 Induces Apoptosis of Human Gastric Cancer SGC-7901 Cells via the Epidermal Growth Factor Receptor (EGFR)/Akt/Nuclear Factor kappa B (NF-κB) Pathway [O] . Wanting Li, Qing Li, Liqun Wei, 2019

机译：rosmarinic酸类似物-11通过表皮生长因子受体（EGFR）/ Akt /核因子Kappa B（NF-κB）途径诱导人胃癌SGC-7901细胞的凋亡

Rosmarinic Acid Analogue-11 Induces Apoptosis of Human Gastric Cancer SGC-7901 Cells via the Epidermal Growth Factor Receptor (EGFR)/Akt/Nuclear Factor kappa B (NF-κB) Pathway

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