IKBKE Upregulation is Positively Associated with Squamous Cell Carcinoma of the Lung In Vivo and Malignant Transformation of Human Bronchial Epithelial Cells In Vitro

摘要

BackgroundThe IκB kinase inhibitor of κB kinase epsilon (IKBKE) is overexpressed in several human cancers. Although IKBKE plays an important role in smoking-induced non-small cell lung cancer carcinogenesis, its role in squamous cell carcinoma of the lung (SCCL) remains unclear.