Correlation Between Nuclear Factor E2-Related Factor 2 Expression and Gastric Cancer Progression

机译：核因子E2相关因子2表达与胃癌进展的相关性

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BackgroundNuclear factor E2-related factor 2 (Nrf2) plays an anti-oxidative and phase II detoxification function via its up-regulation on various antioxidant response elements (ARE) genes. Nrf2 can protect both normal and cancer cells from damages of cell stress, thereby exerting a critical role in the development of cancer. The expression and significance of Nrf2 in gastric cancer, however, has not been reported. This study thus aimed to investigate the expression of Nrf2 in gastric cancer tissues via immunohistochemical (IHC) staining.

机译：背景核因子E2相关因子2（Nrf2）通过上调各种抗氧化剂响应元件（ARE）基因而发挥抗氧化和II期排毒功能。 Nrf2可以保护正常细胞和癌细胞免受细胞压力的损害，从而在癌症的发展中发挥关键作用。然而，尚未报道Nrf2在胃癌中的表达和意义。因此，本研究旨在通过免疫组织化学（IHC）染色研究Nrf2在胃癌组织中的表达。

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期刊名称 Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
作者
Hongyu Zheng; Zhiwei Nong; Guohao Lu;
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作者单位

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年(卷),期 2015(21),-1
年度 2015
页码 2893–2899
总页数 7
原文格式 PDF
正文语种
中图分类
关键词
Gastric Acidity Determination NF-E2-Related Factor 2 Receptors Tumor Necrosis Factor Type I;

机译：胃酸度测定;NF-E2-相关因子2;受体;I型肿瘤坏死因子;

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专利

1. Correlation Between Nuclear Factor E2-Related Factor 2 Expression and Gastric Cancer Progression [J] . Hongyu Zheng, Zhiwei Nong, Guohao Lu Medical science monitor : . 2015,第1期

机译：核因子E2相关因子2表达与胃癌进展的相关性
2. Clinically significant association of elevated expression of nuclear factor E2-related factor 2 expression with higher glucose uptake and progression of upper urinary tract cancer [J] . Akinori Nukui, Takahiro Narimatsu, Tsunehito Kambara, BMC Cancer . 2018,第1期

机译：核因子E2相关因子2表达升高与较高的葡萄糖摄取和上尿路癌进展的临床相关性
3. Correlation between human epidermal growth factor receptor 2 expression level and efficacy of trastuzumab beyond progression in metastatic gastric cancer [J] . Narita Yukiya, Kadowaki Shigenori, Masuishi Toshiki, Oncology letters . 2017,第2aPta2期

机译：人表皮生长因子受体2表达水平与曲妥珠单抗超出转移胃癌进展的相关性和功效的相关性
4. Research on the Factors that Affecting the Occurrence of Gastric Cancer Based on NCBI Gene Expression Omnibus Database [C] . Bowei Liao International Conference on Frontiers of Biological Sciences and Engineering . 2020

机译：基于NCBI基因表达的胃癌发生的因素研究
5. The critical role and regulation of transcription factor FoxM1 in gastric cancer development and progression. [D] . Li, Qiang. 2009

机译：转录因子FoxM1在胃癌发展和进程中的关键作用和调节。
6. Clinically significant association of elevated expression of nuclear factor E2-related factor 2 expression with higher glucose uptake and progression of upper urinary tract cancer [O] . Akinori Nukui, Takahiro Narimatsu, Tsunehito Kambara, 2018

机译：核因子E2相关因子2表达升高与更高的葡萄糖摄取和上尿路癌进展的临床相关性
7. Correlation Between Nuclear Factor E2-Related Factor 2 Expression and Gastric Cancer Progression [O] . Hongyu Zheng, Zhiwei Nong, Guohao Lu 2015

机译：核因子E2相关因子2表达与胃癌进展的相关性
8. Expression of Transforming Growth Factor-Beta (TGF-Beta) in Prostate Cancer Progression [R] . Lee, C. 2003

机译：转化生长因子-β（TGF-β）在前列腺癌进展中的表达

Correlation Between Nuclear Factor E2-Related Factor 2 Expression and Gastric Cancer Progression

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