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Honouring ‘Patient 38’ – a mother of all IVF mothers?

机译:尊重患者38(所有IVF母亲的母亲)?

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摘要

This commentary addresses one aspect of the early history of IVF in Britain. Specific data are re-examined from the recently published, anonymized database of medical records from the Oldham period of research conducted by Robert Edwards, Patrick Steptoe and their team of assistants between 1969 and 1978. By focusing on a reformulation of the ‘scheduled treatment cycles per patient’, attention is drawn to the small, but nevertheless not insignificant, number of subjects who returned to Oldham at least five times or more to undergo innovative procedures and/or receive other experimental treatments over the duration of the research project. These multiple efforts are contrasted with the single or double treatment cycles received by the majority of the infertile women involved, including the only two experiencing live births, Lesley Brown and Grace Montgomery. The re-presented data facilitates new interpretations and raises fresh research questions about the nature of contemporary and present characterisations of the major protagonists in the ‘IVF story’, the identity of those women who originally took part and the origin of and reasons for discrepancies in the records maintained about research subjects.
机译:这篇评论谈到了英国试管婴儿早期历史的一个方面。具体数据从1969年至1978年之间由罗伯特·爱德华兹,帕特里克·斯特普托和他们的助手团队在奥尔德姆时期的医学研究数据库中重新发布,对其进行了匿名检查。通过重点关注“计划治疗周期”的重新制定每位患者的注意力都吸引到了很​​小但并非微不足道的受试者数量,这些受试者在研究项目期间至少经历了五次或更多次返回Oldham接受创新性程序和/或接受其他实验性治疗。这些多重努力与所涉及的大多数不育妇女所接受的单次或两次治疗周期形成对照,其中包括仅有的两个活产婴儿莱斯利·布朗和格蕾丝·蒙哥马利。重新呈现的数据有助于进行新的解释,并提出有关“ IVF故事”中主要主角的当代特征和当前特征,最初参加活动的妇女的身份以及身份差异来源和原因的新研究问题。保留有关研究主题的记录。

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