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Surgical palliation for pancreatic cancer: will biliary bypass alone suffice?

机译:胰腺癌的手术缓解:仅胆道旁路手术就足够了吗?

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摘要

Because a number of options are available to relieve the obstructed bile duct, stomach or both in patients with irresectable carcinoma of the pancreatic head, palliative surgery for this condition was reviewed retrospectively between 1971 and 1981 at the Royal United Hospital, Bath. One hundred and sixty-five patients underwent a biliary bypass procedure with (n = 37), or without (n = 128) gastric drainage. Thirty patients had a prophylactic gastroenterostomy to avoid gastric outlet obstruction: tumour encroachment made gastroenterostomy essential in seven others. After biliary bypass alone, operative mortality was 14%. After a concomitant gastroenterostomy, mortality was 27% (P less than 0.04). Within a year of biliary bypass alone, there was a 9% incidence of gastric outlet obstruction requiring gastric drainage, with an associated mortality rate of 18%. Survival after biliary bypass or biliary bypass with gastroenterostomy was equal (7-8 months). Except where gastric outlet obstruction is imminent, palliation for irresectable pancreatic head carcinomas should be by biliary bypass alone, because the addition of a gastroenterostomy almost doubles the mortality without any advantage in survival time.
机译:由于可采用多种选择来缓解无法切除的胰头癌患者的胆管,胃或两者均受阻,因此,1971年至1981年间,在巴斯的皇家联合医院对这种情况的姑息手术进行了回顾性回顾。 165例患者接受了(n = 37)或不进行(n = 128)胃引流的胆道搭桥手术。 30例患者进行了预防性肠胃造口术,以避免胃出口阻塞:肿瘤侵犯使胃肠道造口术在其他七个患者中至关重要。仅经胆道旁路手术后,手术死亡率为14%。伴随肠胃造口术,死亡率为27%(P小于0.04)。仅在胆道旁路手术的一年内,发生胃排出口阻塞需要胃引流的发生率为9%,相关死亡率为18%。胆道搭桥或胃肠道造口术胆道搭桥后的生存期相等(7-8个月)。除非迫在眉睫的胃出口梗阻,否则不可切除的胰头癌的缓解应仅通过胆道旁路术,因为增加胃肠造口术几乎会使死亡率增加一倍,而对生存时间没有任何好处。

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