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High efficacy of two artemisinin-based combinations: artesunate + sulfadoxine-pyrimethamine and artemether-lumefantrine for falciparum malaria in Yemen

机译：两种基于青蒿素的组合的高效药：青蒿琥酯+磺胺多辛-乙胺嘧啶和青蒿琥酯-氟美汀治疗也门恶性疟疾

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BackgroundArtesunate + sulfadoxine-pyrimethamine (AS + SP) has been the first-line treatment and artemether-lumefantrine (AL) the second-line treatment for uncomplicated falciparum malaria in Yemen since 2005. This paper reports the results of studies conducted to monitor therapeutic efficacy of these two drugs in sentinel sites in Yemen.

机译：自2005年以来，青蒿琥酯+磺胺多辛-乙胺嘧啶（AS + SP）自2005年以来一直是也门单纯性恶性疟疾的一线治疗，而蒿甲醚-卢美他汀（AL）是二线治疗。本文报道了监测治疗效果的研究结果。在也门前哨点的这两种药物中。

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期刊名称 Malaria Journal
作者
Ahmed A. Adeel; Niaz Abdo Saeed; Adel Aljasari; Amar M. Almohager; Mohamed H. Galab; Amar AlMahdi; Mansor H. Mahammed; Mohammed AlDarsi; Yahiya A. Salaeah; Hoda Atta; Ghasem Zamani; Marian Warsame; Amy Barrette; Hanan El Mohammady; Rania A. Nada;
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作者单位

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年(卷),期 2015(14),-1
年度 2015
页码 449
总页数 9
原文格式 PDF
正文语种
中图分类寄生动物、寄生虫学;医学寄生虫学;
关键词
Yemen Artesunate Sulfadoxine-pyrimethamine Anti-malarial drugs Drug resistance Plasmodium falciparum Gametocytaemia Artemether-lumefantrine;

机译：也门;青蒿琥酯;磺胺多辛-乙胺嘧啶;抗疟药;耐药性;恶性疟原虫;配子体细胞增多症;蒿甲醚-荧光黄素;

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专利

1. Comparison of Different Artemisinin-based Combinations for the Treatment of Plasmodium falciparum Malaria in Children in Kigali, Rwanda, an Area of Resistance to Sulfadoxine-Pyrimethamine: Artesunate Plus Sulfadoxine/Pyrimethamine versus Artesunate Plus Sulfamethoxypyrazine/Pyrimethamine [J] . Rulisa Stephen, Gatarayiha Jean Philip, Kabarisa Tharcisse, American Journal of Tropical Medicine and Hygiene . 2007,第4期

机译：卢旺达基加利不同地区以青蒿素为基础的联合用药治疗儿童恶性疟原虫疟疾的比较：对磺胺多辛-乙胺嘧啶有抗药性的地区：青蒿琥酯加磺胺嘧啶/乙胺与青蒿琥酯加磺胺甲氧吡嗪/乙胺嘧啶
2. Comparison of different artemisinin-based combinations for the treatment of Plasmodium falciparum malaria in children in Kigali, Rwanda, an area of resistance to sulfadoxine-pyrimethamine: artesunate plus sulfadoxine/pyrimethamine versus artesunate p [J] . Rulisa S, Gatarayiha JP, Kabarisa T, The American Journal of Tropical Medicine and Hygiene . 2007,第4期

机译：卢旺达基加利不同地区以青蒿素为基础的组合药物治疗儿童恶性疟原虫疟疾的比较，卢卡达是对磺胺多辛-乙胺嘧啶有抗药性的地区：青蒿琥酯加磺胺多辛/乙胺嘧啶与青蒿琥酯p
3. High efficacy of two artemisinin-based combinations (artemether-lumefantrine and artesunate plus amodiaquine) for acute uncomplicated malaria in Ibadan, Nigeria. [J] . Falade CO, Ogundele AO, Yusuf BO, Tropical Medicine and International Health: TM and IH . 2008,第5期

机译：两种基于青蒿素的组合（蒿甲醚-卢美特宁和青蒿琥酯加阿莫地喹）在尼日利亚伊巴丹的急性单纯性疟疾的高效治疗。
4. A case of imported Plasmodium Falciparum chloroquine and Sulfadoxine-Pyrimethamine sensitive in a Finland male presentation [C] . N P D Witari, S Masyeni, N W Rusni Annual Applied Science and Engineering Conference . 2019

机译：芬兰男性介绍的进口疟原虫氯喹和磺基甲胺 - 嘧啶敏感的情况
5. Probing Translational Regulation by the Malaria Parasite Plasmodium falciparum: Applying a Novel In Vitro Assay to Identify Genetic Determinants of Regulation and Identify Small Molecules Exploiting P. falciparum Translation as a Drug Target [D] . Sheridan, Christine Moore. 2018

机译：探究疟疾寄生虫恶性疟原虫的翻译调控：应用新型体外测定方法来鉴定调控的遗传决定因素并鉴定利用恶性疟原虫翻译作为药物靶点的小分子
6. High efficacy of artemether-lumefantrine and declining efficacy of artesunate + sulfadoxine-pyrimethamine against Plasmodium falciparum in Sudan (2010–2015): evidence from in vivo and molecular marker studies [O] . Ahmed A. Adeel, Fahad Awad Ali Elnour, Khalid Abdalmutalab Elmardi, 2016

机译：苏丹对蒿甲醚-氟美林汀的高效治疗和青蒿琥酯+磺胺多辛-乙胺嘧啶对恶性疟原虫的缓解作用（2010-2015年）：体内和分子标记研究的证据
7. High efficacy of two artemisinin-based combinations: artesunate + sulfadoxine-pyrimethamine and artemether-lumefantrine for falciparum malaria in Yemen [O] . Ahmed A. Adeel, Niaz Abdo Saeed, Adel Aljasari, 2015

机译：两种基于青蒿素的组合的高效药：青蒿琥酯+磺胺多辛-乙胺嘧啶和青蒿琥酯-氟美汀治疗也门恶性疟疾

High efficacy of two artemisinin-based combinations: artesunate + sulfadoxine-pyrimethamine and artemether-lumefantrine for falciparum malaria in Yemen

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