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Cellular and humoral immune responses against the Plasmodium vivax MSP-119 malaria vaccine candidate in individuals living in an endemic area in north-eastern Amazon region of Brazil

机译：居住在巴西东北亚马逊地区流行地区的个体对间日疟原虫MSP-119疟疾疫苗候选者的细胞和体液免疫反应

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BackgroundPlasmodium vivax merozoite surface protein-1 (MSP-1) is an antigen considered to be one of the leading malaria vaccine candidates. PvMSP-1 is highly immunogenic and evidences suggest that it is target for protective immunity against asexual blood stages of malaria parasites. Thus, this study aims to evaluate the acquired cellular and antibody immune responses against PvMSP-1 in individuals naturally exposed to malaria infections in a malaria-endemic area in the north-eastern Amazon region of Brazil.

机译：背景间日疟原虫裂殖子表面蛋白-1（MSP-1）是一种抗原，被认为是主要的疟疾疫苗候选者之一。 PvMSP-1具有高度的免疫原性，证据表明它是针对疟原虫无性血液阶段的保护性免疫的靶标。因此，本研究旨在评估巴西东北亚马逊地区疟疾流行区自然暴露于疟疾感染的个体对PvMSP-1获得的细胞和抗体免疫反应。

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期刊名称 Malaria Journal
作者
Evelyn KP Riccio; Paulo RR Totino; Lilian R Pratt-Riccio; Vitor Ennes-Vidal; Irene S Soares; Maurício Martins Rodrigues; José Maria de Souza; Cláudio Tadeu Daniel-Ribeiro; Maria de Fátima Ferreira-da-Cruz;
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年(卷),期 2013(12),-1
年度 2013
页码 326
总页数 15
原文格式 PDF
正文语种
中图分类寄生动物、寄生虫学;医学寄生虫学;
关键词
Malaria Plasmodium vivax MSP-119 Cellular response Antibodies;

机译：疟疾;间日疟原虫;MSP-119;细胞应答;抗体;

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专利

1. Cellular and humoral immune responses against the Plasmodium vivax MSP-119 malaria vaccine candidate in individuals living in a Brazilian endemic area in northeastern Amazon [J] . Evelyn Kety Pratt Riccio, Paulo Renato Rivas Totino, Irene Silva Soares, Malaria Journal . 2014,第S1期

机译：生活在亚马逊东北部巴西流行区的个体对间日疟原虫MSP-119疟疾疫苗候选者的细胞和体液免疫反应
2. Cellular and humoral immune responses against the Plasmodium vivax MSP-1₁₉ malaria vaccine candidate in individuals living in an endemic area in north-eastern Amazon region of Brazil [J] . Evelyn KP Riccio, Paulo RR Totino, Lilian R Pratt-Riccio, Malaria Journal . 2013,第S1期

机译：居住在巴西东北亚马逊地区流行区的人对间日疟原虫MSP-1 _{19 疟疾候选疫苗的细胞和体液免疫反应}
3. Cellular and humoral immune responses against the Plasmodium vivax MSP-1₁₉ malaria vaccine candidate in individuals living in an endemic area in north-eastern Amazon region of Brazil [J] . Evelyn KP Riccio, Paulo RR Totino, Lilian R Pratt-Riccio, Malaria Journal . 2013,第S1期

机译：居住在巴西东北亚马逊地区流行区的人对间日疟原虫MSP-1 _{19 疟疾候选疫苗的细胞和体液免疫反应}
4. Effects of Tunable Degradation on Humoral, Cellular, and Protective Immune Responses Generated by a Universal Flu Vaccine Formulated with Acetalated Dextran Microparticles [C] . Naihan Chen, Michael A. Collier, Matthew D. Gallovic, Society for Biomaterials annual meeting and exposition . 2019

机译：可调节降解对通用流感疫苗配制的醋酸葡聚糖微粒产生的体液，细胞和保护性免疫反应的影响
5. Humoral and cellular immune responses in RNA viral infections: Immunogenicity of HIV-1, HCV and SARS-CoV candidate vaccines in animal models. [D] . Azizi, Ali. 2006

机译：RNA病毒感染中的体液和细胞免疫应答：HIV-1，HCV和SARS-CoV候选疫苗在动物模型中的免疫原性。
6. Cellular and humoral immune responses against the Plasmodium vivax MSP-119 malaria vaccine candidate in individuals living in a Brazilian endemic area in northeastern Amazon [O] . Evelyn Kety Pratt Riccio, Paulo Renato Rivas Totino, Irene Silva Soares, 2014

机译：生活在亚马逊东北部巴西流行区的个体对间日疟原虫MSP-119疟疾疫苗候选者的细胞和体液免疫反应
7. Cellular and humoral immune responses against the Plasmodium vivax MSP-119 malaria vaccine candidate in individuals living in an endemic area in north-eastern Amazon region of Brazil [O] . Riccio, Evelyn K, Totino, Paulo R, Pratt-Riccio, Lilian R, 2015

机译：居住在巴西东北亚马逊地区流行地区的个体对间日疟原虫MSP-119疟疾疫苗候选者的细胞和体液免疫反应
8. Molecular Epidemiology of Epidemic Severe Malaria Caused by Plasmodium vivax in the State of Amazonas, Brazil [R] . Santos-Ciminera, P. D. 2005

机译：巴西亚马逊州间日疟原虫引起的流行性严重疟疾的分子流行病学

Cellular and humoral immune responses against the Plasmodium vivax MSP-119 malaria vaccine candidate in individuals living in an endemic area in north-eastern Amazon region of Brazil

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