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Transmission Dynamics of Resistant Bacteria in a Predator-Prey System

机译:捕食者-食饵系统中抗性细菌的传播动力学。

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摘要

This paper discusses the impact on human health caused by the addition of antibiotics in the feed of food animals. We use the established transmission rule of resistant bacteria and combine it with a predator-prey system to determine a differential equations model. The equations have three steady equilibrium points corresponding to three population dynamics states under the influence of resistant bacteria. In order to quantitatively analyze the stability of the equilibrium points, we focused on the basic reproduction numbers. Then, both the local and global stability of the equilibrium points were quantitatively analyzed by using essential mathematical methods. Numerical results are provided to relate our model properties to some interesting biological cases. Finally, we discuss the effect of the two main parameters of the model, the proportion of antibiotics added to feed and the predation rate, and estimate the human health impacts related to the amount of feed antibiotics used. We further propose an approach for the prevention of the large-scale spread of resistant bacteria and illustrate the necessity of controlling the amount of in-feed antibiotics used.
机译:本文讨论了食用动物饲料中添加抗生素对人体健康的影响。我们使用已建立的抗性细菌传播规则,并将其与捕食者-猎物系统结合起来,以确定微分方程模型。该方程具有三个稳定的平衡点,分别对应于抗性细菌影响下的三个种群动态状态。为了定量分析平衡点的稳定性,我们集中于基本繁殖数。然后,使用基本数学方法定量分析了平衡点的局部和全局稳定性。提供了数值结果,以将我们的模型特性与一些有趣的生物学案例相关联。最后,我们讨论了模型的两个主要参数的影响,即饲料中添加抗生素的比例和捕食率,并估计了与饲料中抗生素用量有关的对人类健康的影响。我们进一步提出了一种预防耐药菌大规模传播的方法,并说明了控制饲料中使用的抗生素数量的必要性。

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