Combination of Pectin and Eudargit RS and Eudragit RL in the Matrix of Pellets Prepared by Extrusion-Spheronization for Possible Colonic Delivery of 5-Amino Salicylic Acid

机译：果胶与Eudargit RS和Eudragit RL的组合在通过挤出滚圆法制备的可能会结肠递送5-氨基水杨酸的药丸基质中

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BackgroundDifferent methods have been studied for targeting drugs to the colon, such as pH-based, time dependent and bacterially degradable systems. However, due to variations in physiological conditions of patients, one system alone could not be completely reliable on colonic drug delivery.

机译：背景已经研究了将药物靶向结肠的不同方法，例如基于pH值，时间依赖性和可细菌降解的系统。但是，由于患者生理状况的变化，仅凭一种系统就无法完全可靠地进行结肠给药。

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期刊名称 Jundishapur Journal of Natural Pharmaceutical Products
作者
Abbas Akhgari; Mohammadreza Abbaspour; Meysam Moradkhanizadeh;
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作者单位

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年(卷),期 2013(8),2
年度 2013
页码 86–92
总页数 7
原文格式 PDF
正文语种
中图分类药学;
关键词
Pectin Methylmethacrylate-methacrylic Acid Copolymer Colonic Diseases Drug Delivery System;

机译：果胶;甲基丙烯酸甲酯-甲基丙烯酸共聚物;结肠疾病;药物输送系统;

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1. Combination of Pectin and Eudargit RS and Eudragit RL in the Matrix of Pellets Prepared by Extrusion-Spheronization for Possible Colonic Delivery of 5-Amino Salicylic Acid [J] . Abbas Akhgari, Meysam Moradkhanizadeh, Mohammadreza Abbaspour Jundishapur Journal of Natural Pharmaceutical Products . 2013,第2期

机译：果胶与Eudargit RS和Eudragit RL的组合在通过挤出滚圆法制备的可能会结肠递送5-氨基水杨酸的药丸基质中
2. Studies of pectin HM/Eudragit RL/Eudragit NE film-coating formulations intended for colonic drug delivery. [J] . Semde R, Amighi K, Devleeschouwer MJ, International Journal of Pharmaceutics . 2000,第1a2期

机译：果胶HM / Eudragit RL / Eudragit NE膜包衣制剂用于结肠药物递送的研究。
3. pH-Sensitive Eudragit S-100 Coated Chitosan Nanoparticles of 5-Amino Salicylic Acid for Colon Delivery [J] . Mongia Pooja, Khatik Renuka, Raj Rakesh, Journal of biomaterials and tissue engineering . 2014,第9期

机译：pH敏感的Eudragit S-100包覆的5-氨基水杨酸壳聚糖纳米颗粒用于结肠递送。
4. Effect of ca to salicylic acid release in pectin based controlled drug delivery system [C] . L Kistriyani, S K Wirawan, W B Sediawan International Conference on Engineering and Technology for Sustainable Development . 2016

机译：Ca至水杨酸释放在果胶基受控药物递送系统中的影响
5. Physical-mechanical characterization of Eudragit polymers and their application in extended-release matrix tablets prepared via roller compaction. [D] . Dave, Vivek S. 2009

机译：Eudragit聚合物的物理机械特性及其在通过辊压成型制备的缓释基质片剂中的应用。
6. The effect of pectin on swelling and permeability characteristics of free films containing Eudragit RL and/or RS as a coating formulation aimed for colonic drug delivery [O] . A. Akhgari, F. Farahmand, H. Afrasiabi Garekani, 2010

机译：果胶对包含Eudragit RL和/或RS作为用于结肠药物递送的包衣制剂的自由膜的溶胀和渗透特性的影响
7. Combination of Pectin and Eudargit RS and Eudragit RL in the Matrix of Pellets Prepared by Extrusion-Spheronization for Possible Colonic Delivery of 5-Amino Salicylic Acid [O] . Abbas Akhgari, Mohammadreza Abbaspour, Meysam Moradkhanizadeh 2013

机译：果胶和eudargit Rs和Eudragit R1在通过挤出 - 球形制备的颗粒基质中的组合，用于5-氨基水杨酸的结肠递送

Combination of Pectin and Eudargit RS and Eudragit RL in the Matrix of Pellets Prepared by Extrusion-Spheronization for Possible Colonic Delivery of 5-Amino Salicylic Acid

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