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A Study for Tooth Bleaching via Carbamide Peroxide-Loaded Hollow Calcium Phosphate Spheres

机译:负载过氧化碳酰胺的空心磷酸钙球对牙齿漂白的研究

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摘要

The objective of this study was to investigate if a prolonged bleaching effect of carbamide peroxide-loaded hollow calcium phosphate spheres (HCPS) can be achieved. HCPS was synthesized via a hydrothermal reaction method. Carbamide peroxide (CP) was-loaded into HCPS by mixing with distilled water as solvent. We developed two bleaching gels containing CP-loaded HCPS: one gel with low HP concentration as at-home bleaching gel, and one with high HP concentration as in-office gel. Their bleaching effects on stained human permanent posterior teeth were investigated by measuring the color difference before and after bleaching. The effect of gels on rhodamine B degradation was also studied. To investigate the potential effect of remineralization of using HCPS, bleached teeth were soaked in phosphate buffer solution (PBS) containing calcium and magnesium ions. Both bleaching gels had a prolonged whitening effect, and showed a strong ability to degrade rhodamine B. After soaking in PBS for 3 days, remineralization was observed at the sites where HCPS attached to the teeth surface. CP-loaded HCPS could prolong the HP release behavior and improve the bleaching effect. HCPS was effective in increasing the whitening effect of carbamide peroxide and improving remineralization after bleaching process.
机译:这项研究的目的是调查是否可以达到延长过氧化脲负载空心磷酸钙球(HCPS)的漂白效果的目的。 HCPS是通过水热反应法合成的。通过与作为溶剂的蒸馏水混合,将过氧化脲(CP)装入HCPS。我们开发了两种包含CP负载的HCPS的漂白凝胶:一种低HP浓度的凝胶作为家用漂白凝胶,另一种高HP浓度的凝胶作为办公室凝胶。通过测量漂白前后的色差,研究了它们对染色后的人类永久后牙的漂白效果。还研究了凝胶对若丹明B降解的影响。为了研究使用HCPS进行再矿化的潜在效果,将漂白的牙齿浸泡在含有钙和镁离子的磷酸盐缓冲溶液(PBS)中。两种漂白凝胶均具有延长的增白效果,并且显示出强大的降解罗丹明B的能力。在PBS中浸泡3天后,在HCPS附着在牙齿表面的部位观察到再矿化。 CP负载的HCPS可以延长HP的释放行为并改善漂白效果。 HCPS可有效提高过氧化脲的增白效果,并改善漂白过程后的再矿化作用。

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