mRNAs expression profiles of high glucose-induced memory in human umbilical vein endothelial cells

摘要

PurposeA long-term “memory” of hyperglycemic stress, even when glycemia is normalized, has been previously reported in endothelial cells. However, the molecular mechanism of “metabolic memory” (MM) remains unknown. In this report, we sought to screen at the whole transcriptome level the genes that participate in MM.