Pharmacokinetic comparison of a fixed-dose combination versus concomitant administration of fimasartan amlodipine and rosuvastatin using partial replicated design in healthy adult subjects

摘要

ObjectiveThe aim of this study was to compare the pharmacokinetics (PK) and safety profiles of a fixed-dose combination (FDC) formulation of fimasartan, amlodipine, and rosuvastatin with the co-administration of the two products by using a replicated crossover study design in healthy male subjects.