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Clinical outcomes of the resect and discard strategy using magnifying narrow-band imaging for small ( 10 mm) colorectal polyps

机译:使用放大窄带成像技术治疗小(10mm)结直肠息肉的切除并丢弃策略的临床结果

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摘要

>Background and study aim  The “resect and discard” strategy is a new paradigm for the management of small colorectal polyps that reduces the cost and effort related to pathological diagnosis after polypectomy. This retrospective study aimed to clarify the clinical outcome of the “resect and discard” strategy for small colorectal polyps. >Patients and methods  The clinical records were reviewed from 501 consecutive patients who underwent the “resect and discard” strategy for colorectal polyps smaller than 10 mm at our hospital between January 2008 and December 2010. All colorectal lesions were evaluated onsite under magnifying narrow-band imaging after careful conventional white-light imaging. In cases of low grade adenoma predicted with high confidence, colonoscopists selected the “resect and discard” option without formal histopathology. The mid-term outcomes were evaluated to validate the curability of the “resect and discard” strategy. >Results  The present study included 501 consecutive patients with 816 lesions. The mid-term outcomes were examined for 476 (95 %) patients who received follow-up for at least 1 year after undergoing the “resect and discard” strategy. The median observation period was 83 months (range 12 – 117 months). No patient died from colorectal cancer related to the procedure, resulting in a disease-specific survival rate of 100 %. There were no local and/or distant recurrences detected during follow-up. >Conclusions  The “resect and discard” strategy for small colorectal polyps under strict preoperative diagnosis achieves excellent mid-term outcome.
机译:>背景和研究目的“切除并丢弃”策略是一种处理大肠息肉的新范例,可减少息肉切除术后病理诊断的成本和精力。这项回顾性研究旨在阐明小肠息肉“切除并丢弃”策略的临床结果。 >患者和方法于2008年1月至2010年12月在我院对501例小于10mm的大肠息肉行“切除并丢弃”策略的501例患者的临床记录进行了回顾。对所有大肠病变进行了评估仔细的常规白光成像后,在放大的窄带成像下进行现场成像。对于高信度预测的低度腺瘤,结肠镜检查者选择“切除并丢弃”选项,而无需进行正式的组织病理学检查。对中期结果进行了评估,以验证“切除并丢弃”策略的可治愈性。 >结果本研究包括501例连续的816个病变患者。对接受“切除并丢弃”策略后至少随访一年的476名(95%)患者进行了中期检查。中位观察期为83个月(范围12±117个月)。没有患者死于与该手术相关的大肠癌,导致疾病特异性存活率为100%。随访期间未发现局部和/或远处复发。 >结论在严格的术前诊断下,结直肠小息肉的“切除并丢弃”策略取得了良好的中期效果。

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