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Is an iris claw IOL a good option for correcting surgically induced aphakia in children? A review of the literature and illustrative case study

机译:虹膜爪人工晶体是矫正儿童手术性无晶状体的好选择吗?文献综述和案例研究

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摘要

Refractive correction of aphakia in childhood can be a complex management issue following lensectomy for congenital cataract or ectopia lentis. Some children have inadequate capsular support to allow an ‘in the bag' or sulcus fixated intra-ocular lens (IOL). In such cases, options for refractive correction include spectacles, contact lenses, or surgically fixed IOLs. Many methods of IOL fixation have been described, but none are widely adopted in children. In recent years, the iris-fixated Artisan Aphakic IOL has gained popularity, but there is still significant concern about the rate of corneal endothelial cell loss and IOL de-enclavation. Here, we review the current literature on the use of iris-fixated IOLs in children, the published data on endothelial cell loss and de-enclavation rates. We present a case illustrating the significant improvements in quality of life, which can be seen in selected children, and also the rate of endothelial cell loss, which can be encountered after initial surgery, and a re-enclavation event. We make the case that until more data are available on normal endothelial cell decline in early childhood, in addition to age-specific rates of endothelial cell loss and de-enclavation rates following surgery, the use of iris-fixated IOLs in children will continue to be a moot point and is unlikely to be widely adopted.
机译:对于先天性白内障或轻度外翻,在晶状体摘除术后,对儿童无晶状体进行屈光矫正可能是一个复杂的管理问题。一些孩子的囊膜支持不足,无法“固定”或固定沟内人工晶状体(IOL)。在这种情况下,屈光矫正的选择包括眼镜,隐形眼镜或手术固定的IOL。已经描述了许多人工晶状体固定的方法,但没有一种在儿童中被广泛采用。近年来,虹膜固定的Artisan Aphakic IOL受到欢迎,但是,对于角膜内皮细胞丢失和IOL脱离包膜的速度仍存在重大担忧。在这里,我们回顾了有关在儿童中使用虹膜固定人工晶状体的最新文献,有关内皮细胞损失和去囊化率的公开数据。我们提供了一个案例,说明在选定的儿童中可以看到生活质量的显着改善,以及在初次手术和再次包埋事件后可能会遇到的内皮细胞损失率。我们认为,除非有更多关于儿童早期正常内皮细胞减少的数据,除了特定年龄段的内皮细胞丢失率和手术后的去包膜率,在儿童中使用虹膜固定人工晶状体将继续尚无定论,不太可能被广泛采用。

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