BackgroundAutonomously replicating sequences (ARSs) function as replication origins in Saccharomyces cerevisiae. ARSs contain the 17 bp ARS consensus sequence (ACS), which binds the origin recognition complex. The yeast genome contains more than 10,000 ACS matches, but there are only a few hundred origins, and little flanking sequence similarity has been found. Thus, identification of origins by sequence alone has not been possible.
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机译：背景自主复制序列（ARS）用作酿酒酵母中的复制起点。 ARS包含17 bp ARS共有序列（ACS），该序列与起源识别复合体结合。酵母基因组包含10,000多个ACS匹配，但是只有几百个起源，并且几乎没有发现侧翼序列相似性。因此，不可能仅通过序列来鉴定来源。
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