Extracting biological information from DNA arrays: an unexpected link between arginine and methionine metabolism in Bacillus subtilis

摘要

BackgroundIn global gene expression profiling experiments, variation in the expression of genes of interest can often be hidden by general noise. To determine how biologically significant variation can be distinguished under such conditions we have analyzed the differences in gene expression when Bacillus subtilis is grown either on methionine or on methylthioribose as sulfur source.