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Studies on the Nature and Function of Polygenic Loci in Drosophila. III. Veinlet Modifiers Having Region-Specific Effects upon the Vein Pattern

机译:果蝇中多基因位点的性质和功能研究。三静脉修饰剂对静脉图案具有特定区域的影响

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摘要

Polygenic modifiers affecting the expression of the mutant veinlet were studied to determine whether each acts specifically upon one vein or wing region or whether they affect the venation pattern in some general way. Selection experiments showed that the L4 vein can be modified independently of the L2 and L3 veins. Similarly, the L2 vein can be shortened while the L3 is selected to be longer, although there is some interdependence between the L2 and L3 veins. Assays of heterozygous whole chromosome effects show that different chromosomes are involved in the responses of separate veins, and one polygenic locus causing a decrease in L4 vein length has been isolated. Substitutions of whole chromosomes from selection lines into unselected backgrounds of non-homologous mutants demonstrate that the selected modifiers have the same qualitative effects upon other mutants having similar phenotypes. These results support the hypothesis that the polygenic modifiers affecting veinlet expression function independently of the veinlet locus, presumably by influencing common steps in the developmental processes leading to the formation of individual veins.
机译:研究了影响突变体小静脉表达的多基因修饰剂,以确定每种修饰剂是否特异性作用于一条静脉或翅膀区域,或者它们是否以某种一般方式影响通气模式。选择实验表明,L4静脉可以独立于L2和L3静脉进行修饰。类似地,尽管L2和L3静脉之间存在某些相互依赖性,但是L2静脉可以缩短而L3可以选择更长。杂合全染色体效应的分析表明,不同的染色体参与了不同静脉的反应,并且已经分离出一种导致L4静脉长度减少的多基因位点。将整个染色体从选择系代入非同源突变体的未选择背景表明,所选择的修饰子对具有相似表型的其他突变体具有相同的定性作用。这些结果支持这样的假设,即影响小静脉表达的多基因修饰子独立于小静脉的位置起作用,大概是通过影响导致单个静脉形成的发育过程中的共同步骤。

著录项

  • 期刊名称 Genetics
  • 作者

    James N. Thompson Jr.;

  • 作者单位
  • 年(卷),期 1975(81),2
  • 年度 1975
  • 页码 387–402
  • 总页数 16
  • 原文格式 PDF
  • 正文语种
  • 中图分类 遗传学;
  • 关键词

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