首页> 美国卫生研究院文献>Gut and Liver >Mest Attenuates CCl4-Induced Liver Fibrosis in Rats by Inhibiting the Wnt/β-Catenin Signaling Pathway

【2h】

Mest Attenuates CCl4-Induced Liver Fibrosis in Rats by Inhibiting the Wnt/β-Catenin Signaling Pathway

机译：Mest通过抑制Wnt /β-Catenin信号传导通路减轻CCl4诱导的大鼠肝纤维化

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

Background/AimsThe Wnt/β-catenin signaling pathway has been reported to play an important role in liver fibrosis. This study was designed to investigate whether mesoderm-specific transcript homologue (Mest), a strong negative regulator of Wnt/β-catenin signaling, could inhibit liver fibrosis.

机译：背景/目的据报道，Wnt /β-catenin信号通路在肝纤维化中起重要作用。这项研究旨在调查中胚层特异性转录本同源物（Mest），Wnt /β-catenin信号的强负调控剂是否可以抑制肝纤维化。

著录项

期刊名称 Gut and Liver
作者
Wenting Li; Chuanlong Zhu; Yi Li; Quan Wu; Rentao Gao;
展开▼
作者单位

展开▼
年(卷),期 2014(8),3
年度 2014
页码 282–291
总页数 10
原文格式 PDF
正文语种
中图分类肠道病毒与肝炎病毒;肝及胆疾病;肠疾病;
关键词
Mesoderm-specific transcript homologue Liver cirrhosis Wnt/β-catenin Hepatic stellate cell;

机译：中胚层特异性转录本同源物;肝硬化;Wnt /β-catenin;肝星状细胞;

相似文献

外文文献
中文文献
专利

1. Mest Attenuates CCl4-Induced Liver Fibrosis in Rats by Inhibiting the Wnt/β-Catenin Signaling Pathway [J] . Wenting Li, Chuanlong Zhu, Yi Li, Gut and Liver . 2014,第3期

机译：Mest通过抑制Wnt /β-Catenin信号传导通路减轻CCl4诱导的大鼠肝纤维化
2. Octreotide attenuates hepatic fibrosis and hepatic stellate cells proliferation and activation by inhibiting Wnt/beta-catenin signaling pathway, c-Myc and cyclin D1 [J] . Zhang Chong, Liu Xue-Qi, Sun Hao-Nan, International immunopharmacology . 2018,第期

机译：通过抑制WNT /β-连环蛋白信号传导途径，C-MYC和Cyclin D1，奥雷妥陶器衰减肝纤维化和肝星状细胞增殖和活化
3. Inhibition of canonical WNT signaling pathway by beta-catenin/CBP inhibitor ICG-001 ameliorates liver fibrosis in vivo through suppression of stromal CXCL12 [J] . Akcora Busra Ozturk, Storm Gert, Bansal Ruchi Biochimica et biophysica acta. Molecular basis of disease: BBA . 2018,第3期

机译：通过β-连环蛋白/ CBP抑制剂ICG-001抑制规范WNT信号传导途径，通过抑制基质CXCL12来改善体内肝纤维化
4. Model Reduction and Analysis of Robustness for the Wnt/βCatenin Signal Transduction Pathway [C] . Rol, Kriiger, Reinhart Heinrich International Workshop on Bioinformatics and Systems Biology . 2004

机译：WNT /βCatenin信号转导途径的模型还原与鲁棒性分析
5. Elucidating the Roles of Wnt/Beta-Catenin Signaling in Liver Disease, Cancer, and Regeneration [D] . Preziosi, Morgan Elizabeth. 2018

机译：阐明Wnt /β-连环蛋白信号传导在肝病，癌症和再生中的作用
6. Overexpression of miR-27b-3p Targeting Wnt3a Regulates the Signaling Pathway of Wnt/β-Catenin and Attenuates Atrial Fibrosis in Rats with Atrial Fibrillation [O] . Xiangwei Lv, Jinyi Li, Yisen Hu, 2019

机译：靶向Wnt3a的miR-27b-3p的过表达调节心房纤颤大鼠Wnt /β-Catenin的信号通路并减轻其心房纤维化
7. Inhibition of canonical WNT signaling pathway by β-catenin/CBP inhibitor ICG-001 ameliorates liver fibrosis in vivo through suppression of stromal CXCL12 [O] . Büsra Öztürk Akcora, Gert Storm, Ruchi Bansal 2018

机译：通过β-catenin / cbp抑制剂Icg-001抑制规范Wnt信号传导途径ICG-001通过抑制基质CXCL12来改善体内肝纤维化

Mest Attenuates CCl4-Induced Liver Fibrosis in Rats by Inhibiting the Wnt/β-Catenin Signaling Pathway

摘要

著录项

相似文献

相关主题

期刊订阅